Evidence map›Paper›PMID 33256672›Full record

ArticleBMC psychiatry2020

The use of the Hungarian Test Your Memory (TYM-HUN), MMSE, and ADAS-Cog tests for patients with mild cognitive impairment (MCI) in a Hungarian population: a cross-sectional study.

Szabolcs Garbóczy, Éva Magócs, Gergő József Szőllősi, Szilvia Harsányi, Anikó Égerházi, László Róbert Kolozsvári

Abstract read
In one paragraph

Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Szabolcs GarbóczyGyula Kenézy University Hospital, Department of Adult Psychiatry, University of Debrecen, Debrecen, Hungary.
Éva MagócsDepartment of Psychiatry, Clinical Center, University of Debrecen, Debrecen, Hungary.
Gergő József SzőllősiDepartment of Family and Occupational Medicine, Faculty of Public Health, University of Debrecen, Postal Adress: Móricz Zs. krt. 22, Debrecen, 4032, Hungary.
Szilvia HarsányiFaculty of Public Health, University of Debrecen, Debrecen, Hungary.
Anikó ÉgerháziDepartment of Psychiatry, Clinical Center, University of Debrecen, Debrecen, Hungary.
László Róbert KolozsváriDepartment of Family and Occupational Medicine, Faculty of Public Health, University of Debrecen, Postal Adress: Móricz Zs. krt. 22, Debrecen, 4032, Hungary. kolozsvari.laszlo@sph.unideb.hu.ORCID 0000-0001-9426-0898

Funding

none none
6 · The paper itself

Abstract

backgroundMild cognitive impairment (MCI) often presages the development of Alzheimer's disease (AD). Accurate and early identification of cognitive impairment will substantially reduce the burden on the family and alleviate the costs for the whole society. There is a need for testing methods that are easy to perform even in a general practitioner's office, inexpensive and non-invasive, which could help the early recognition of mental decline. We have selected the Test Your Memory (TYM), which has proven to be reliable for detecting AD and MCI in several countries. Our study was designed to test the usability of the Hungarian version of the TYM (TYM-HUN) comparing with the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) in MCI recognition in the Hungarian population.

methodsTYM test was translated and validated into Hungarian (TYM-HUN) in a previous study. The TYM-HUN test was used in conjunction with and compared with the MMSE and the ADAS-Cog. For our study, 50 subjects were selected: 25 MCI patients and 25 healthy controls (HC). Spearman's rank correlation was used to analyse the correlation between the scores of MMSE and ADAS-Cog with TYM-HUN and the receiver operating characteristic (ROC) curve was established.

resultsMCI can be distinguished from normal aging using TYM-HUN. We established a 'cut-off' point of TYM-HUN (44/45points) where optimal sensitivity (80%) and specificity (96%) values were obtained to screen MCI. The total TYM-HUN scores significantly correlated with the MMSE scores (ρ = 0.626; p < 0.001) and ADAS-Cog scores (ρ = - 0.723; p < 0.001).

conclusionsOur results showed that the TYM-HUN is a reliable, fast, self-administered questionnaire with the right low threshold regarding MCI and can be used for the early diagnosis of cognitive impairment.

Indexed as

Alzheimer DiseaseCognitive DysfunctionCross-Sectional StudiesHumansHungaryNeuropsychological TestsSensitivity and SpecificityAlzheimer’s diseaseDementiaDiagnosisEarly detectionMild cognitive impairmentTest

Identifiers

PMID33256672
PMCPMC7708165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.