ArticleBMC pregnancy and childbirth2020
Changing trends of birth weight with maternal age: a cross-sectional study in Xi'an city of Northwestern China.
Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 66 citations in OpenAlex.
- Analysis of early morbidity and outcomes in macrosomic newborns.BMC pregnancy and childbirth · 2026Article
- Assessing the impact of China's universal two-child policy on infant health: evidence from a quasi-experimental study.European journal of public health · 2026Article
- Advanced maternal age at first delivery and long-term maternal risk for endocrine morbidity.Archives of gynecology and obstetrics · 2026Article
- Impact of Bariatric Surgery on Newborn Growth Parameters.International journal of pediatrics · 2026Article
- Effect of advanced maternal age on the risk of adverse birth outcomes: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Effects of Liver Enzyme Levels During Pregnancy on Birth Weight.Maternal and child health journal · 2025Article
- Prediction of birthweight with early and mid-pregnancy antenatal markers utilising machine learning and explainable artificial intelligence.Scientific reports · 2025Article
- Predictors of delivery at 48 hours or more in pregnant women with preterm prelabor rupture of membrane: A retrospective cohort study.European journal of obstetrics & gynecology and reproductive biology: X · 2025Article
- Analysis of the influence of advanced maternal age on gestational and fetal outcomes.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Observational
- Paternal age and neonatal outcomes: a population-based cohort study.Human reproduction open · 2025Article
- Impact of prenatal depression, anxiety and stress on low birth weight: a retrospective case-control study in Karachi, Pakistan.BMJ public health · 2025Article
- Gestational diabetes mellitus in previous pregnancy associated with the risk of large for gestational age and macrosomia in the second pregnancy.Frontiers in endocrinology · 2025Article
- Greenspace Morphology and Preterm Birth: A State-Wide Study in Georgia, United States (2001-2016).Environmental health perspectives · 2024Article
- Maternal dietary patterns during pregnancy and birth weight: a prospective cohort study.Nutrition journal · 2024Article
- Prevalence and determinants of suspected developmental delays among 12-month-old children in northeast of Iran: a large-scale population-based study.BMJ paediatrics open · 2024Article
- Associations between maternal dietary intake and nutritional status with fetal growth at 14 to 26 weeks gestation: a cross- sectional study.BMC nutrition · 2024Article
- Cord Blood Proteomic Profiles, Birth Weight, and Early Life Growth Trajectories.JAMA network open · 2024Article
- Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight.Nature communications · 2024Article
- The association between parental age differences and perinatal outcomes.Human reproduction (Oxford, England) · 2024Article
- Determinants of advanced age pregnancy in Ethiopian; multi-level analysis of Ethiopian demographic health survey 2016.PloS one · 2024Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundMost studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of maternal age and birth weight remains unclear. The study aimed to analyze the specific association between maternal age and birth weight.
methodsRaw data for all live births from 2015 to 2018 were obtained from the Medical Birth Registry of Xi'an, China. A total of 490,143 mother-child pairs with full-term singleton live births and the maternal age ranging from 20 to 40 years old were included in our study. Birth weight, gestational age, neonatal birth date, maternal birth date, residence and ethnicity were collected. Generalized additive model and two-piece wise linear regression model were used to analyze the specific relationships between maternal age and birth weight, risk of low birth weight, and risk of macrosomia.
resultsThe relationships between maternal age and birth weight, risk of low birth weight, and risk of macrosomia were nonlinear. Birth weight increased 16.204 g per year when maternal age was less than 24 years old (95%CI: 14.323, 18.086), and increased 12.051 g per year when maternal age ranged from 24 to 34 years old (95%CI: 11.609, 12.493), then decreased 0.824 g per year (95% CI: -3.112, 1.464). The risk of low birth weight decreased with the increase of maternal age until 36 years old (OR = 0.917, 95%CI: 0.903, 0.932 when maternal age was younger than 27 years old; OR = 0.965, 95%CI: 0.955, 0.976 when maternal age ranged from 27 to 36 years old), then increased when maternal age was older than 36 years old (OR = 1.133, 95%CI: 1.026, 1.250). The risk of macrosomia increased with the increase of maternal age (OR = 1.102, 95%CI: 1.075, 1.129 when maternal age was younger than 24 years old; OR = 1.065, 95%CI: 1.060, 1.071 when maternal age ranged from 24 to 33 years old; OR = 1.029, 95%CI: 1.012, 1.046 when maternal age was older than 33 years old).
conclusionsFor women of childbearing age (20-40 years old), the threshold of maternal age on low birth weight was 36 years old, and the risk of macrosomia increased with the increase of maternal age.
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