Evidence map›Paper›PMID 33256643›Full record

ArticleBMC infectious diseases2020

A nomogramic model based on clinical and laboratory parameters at admission for predicting the survival of COVID-19 patients.

Xiaojun Ma, Huifang Wang, Junwei Huang, Yan Geng, Shuqi Jiang, Qiuping Zhou, Xuan Chen, Hongping Hu, Weifeng Li, Chengbin Zhou and 3 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiaojun MaDepartment of Infectious Diseases, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong Province, China.
Huifang WangDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Junwei HuangDepartments of Respiratory and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Zhongshan 2nd Road NO.106, Guangzhou, 510080, Guangdong, China.
Yan GengDepartment of Digestive, NO. 923 Hospital of Joint Service Supporting Force, Nanning, 530021, Guangxi, China.
Shuqi JiangSchool of Medicine, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou, 510006, Guangdong, China.
Qiuping ZhouSchool of Medicine, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou, 510006, Guangdong, China.
Xuan ChenShantou University Medical College, 243 Daxue Road, Shantou, 5105063, Guangdong, China.
Hongping HuDepartment of Emergency, Wuhan Hankou Hospital, 2273 Jiefang Avenue, Wuhan, 430010, Hubei, China.
Weifeng LiDepartment of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Chengbin ZhouDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Xinglin GaoDepartments of Respiratory and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Zhongshan 2nd Road NO.106, Guangzhou, 510080, Guangdong, China.
Na PengDepartment of Critical Care Medicine, General Hospital of Southern Theater Command of PLA, Guangzhou, 510010, Guangdong, China. pnatz@163.com.
Yiyu DengDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. yiyudeng666@163.com.

Funding

High-level Hospital Construction Project of Guangdong Provincial People's Hospital DFJH202002Outstanding Young Medical Talents in Guangdong Province KJ012019435Science and Technology Program of Guangzhou, China 202002030094The Science and Technology Project of Guangdong Province 2019A1515010206
6 · The paper itself

Abstract

backgroundCOVID-19 has become a major global threat. The present study aimed to develop a nomogram model to predict the survival of COVID-19 patients based on their clinical and laboratory data at admission.

methodsCOVID-19 patients who were admitted at Hankou Hospital and Huoshenshan Hospital in Wuhan, China from January 12, 2020 to March 20, 2020, whose outcome during the hospitalization was known, were retrospectively reviewed. The categorical variables were compared using Pearson's χ

resultsA total of 262 patients (134 surviving and 128 non-surviving patients) were included in the analysis. Seven variables, which included age (relative risk [RR]: 0.905, 95% confidence interval [CI]: 0.868-0.944; P < 0.001), chronic heart disease (CHD, RR: 0.045, 95% CI: 0.0097-0.205; P < 0.001, the percentage of lymphocytes (Lym%, RR: 1.125, 95% CI: 1.041-1.216; P = 0.0029), platelets (RR: 1.008, 95% CI: 1.003-1.012; P = 0.001), C-reaction protein (RR: 0.982, 95% CI: 0.973-0.991; P < 0.001), lactate dehydrogenase (LDH, RR: 0.993, 95% CI: 0.990-0.997; P < 0.001) and D-dimer (RR: 0.734, 95% CI: 0.617-0.879; P < 0.001), were identified as the independent risk factors. The nomogram model based on these factors exhibited a good discrimination, with an AUC of 0.948 (95% CI: 0.923-0.973).

conclusionsA nomogram based on age, CHD, Lym%, platelets, C-reaction protein, LDH and D-dimer was established to accurately predict the prognosis of COVID-19 patients. This can be used as an alerting tool for clinicians to take early intervention measures, when necessary.

Indexed as

NomogramsPandemicsPatient AdmissionAdultAgedAged, 80 and overChinaChronic DiseaseComorbidityCOVID-19C-Reactive ProteinFemaleFibrin Fibrinogen Degradation ProductsHeart DiseasesHumansLymphocytesC-Reactive ProteinFibrin Fibrinogen Degradation Productsfibrin fragment DCOVID-19NomogramPrediction modelRisk factorSARS-CoV-2

Identifiers

PMID33256643
PMCPMC7702207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.