Evidence map›Paper›PMID 33256556›Full record

ArticleEmerging microbes & infections2021

Blood transcriptomics to characterize key biological pathways and identify biomarkers for predicting mortality in melioidosis.

Thatcha Yimthin, Jacqueline Margaret Cliff, Rungnapa Phunpang, Peeraya Ekchariyawat, Taniya Kaewarpai, Ji-Sook Lee, Clare Eckold, Megan Andrada, Ekkachai Thiansukhon, Kittisak Tanwisaid and 11 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Effects of exercise on whole-blood transcriptome profile in children with overweight/obesity.American journal of human biology : the official journal of the Human Biology Council · 2024
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Burkholderia pseudomallei and melioidosis.Nature reviews. Microbiology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 13 institutions in 4 countries.

Thatcha YimthinFaculty of Tropical Medicine, Department of Microbiology and Immunology, Mahidol University, Bangkok, Thailand.
Jacqueline Margaret CliffFaculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, UK.
Rungnapa PhunpangFaculty of Tropical Medicine, Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
Peeraya EkchariyawatFaculty of Tropical Medicine, Department of Microbiology and Immunology, Mahidol University, Bangkok, Thailand.
Taniya KaewarpaiFaculty of Tropical Medicine, Department of Microbiology and Immunology, Mahidol University, Bangkok, Thailand.
Ji-Sook LeeFaculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, UK.
Clare EckoldFaculty of Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
Megan AndradaDepartment of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Ekkachai ThiansukhonDepartment of Medicine, Udon Thani Hospital, Udon Thani, Thailand.
Kittisak TanwisaidDepartment of Medicine, Nakhon Phanom Hospital, Nakhon Phanom, Thailand.
Somchai ChuananontDepartment of Medicine, Nakhon Phanom Hospital, Nakhon Phanom, Thailand.
Chumpol MorakotDepartment of Medicine, Mukdahan Hospital, Mukdahan, Thailand.
Narongchai SangsaDepartment of Medicine, Roi Et Hospital, Roi Et, Thailand.
Wirayut SilakunDepartment of Medicine, Buriram Hospital, Buriram, Thailand.
Sunee ChayangsuDepartment of Medicine, Surin Hospital, Surin, Thailand.
Noppol BuasiDepartment of Medicine, Sisaket Hospital, Sisaket, Thailand.
Nicholas DayFaculty of Tropical Medicine, Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
Ganjana LertmemongkolchaiFaculty of Associated Medical Science, Department of Clinical Immunology, Khon Kaen University, Khon Kaen, Thailand.
Wasun ChantratitaFaculty of Medicine Ramathibodi Hospital, Center for Medical Genomics, Mahidol University, Bangkok, Thailand.
T Eoin WestDivision of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-5503-7204
Narisara ChantratitaFaculty of Tropical Medicine, Department of Microbiology and Immunology, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0003-3906-7379
Mahidol University · THLondon School of Hygiene & Tropical Medicine · GBNakhon Phanom University · THArdahan University · TRBuriram Rajabhat University · THImperial College London · GBKhon Kaen University · THRoi et Rajabhat University · THSisaket Rajabhat University · THSurin Hospital · THUdon Thani Hospital · THUniversity of Hawaiʻi at Mānoa · USUniversity of Washington · US

Funding

Determinants of Outcome and Recurrent Infections in MelioidosisU01AI115520 · NIAID · MAHIDOL UNIVERSITY · PI CHANTRATITA, NARISARA, WEST, TIMOTHY EOIN · 2015 to 2019
$2.0M
NIAID NIH HHS U01 AI115520
6 · The paper itself

Abstract

Melioidosis is an often lethal tropical disease caused by the Gram-negative bacillus,

Indexed as

Gene Regulatory NetworksAdultAgedAged, 80 and overBiomarkersCase-Control StudiesFemaleGene Expression ProfilingGene Expression RegulationHumansMaleMelioidosisMiddle AgedProspective StudiesSequence Analysis, RNASurvival AnalysisBiomarkersbiomarkersBurkholderia pseudomalleiimmune responsemelioidosisoutcomeRNA-sequencingtranscriptomics

Identifiers

PMID33256556
PMCPMC7832033
OpenAlexW3110594958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.