Evidence map›Paper›PMID 33256287›Full record

ArticleZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2020

[Research progress of hepatocyte transplantation treatment for alpha-1 antitrypsin deficiency].

W J Xu, J F Xiao, Y M Chen, J Q Ding

Open access · greenAbstract read
In one paragraph

Article in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. [Progress in basic research and clinical application of hepatocyte transplantation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

W J XuDepartment of Infectious Diseases, Southwest Hospital Third Military Medical University(Army Medical University), Chongqing 400038, China.
J F XiaoInstitute of Pathology, Southwest Hospital Third Military Medical University(Army Medical University), Chongqing 400038, China.
Y M ChenInstitute of Pathology, Southwest Hospital Third Military Medical University(Army Medical University), Chongqing 400038, China.
J Q DingDepartment of Infectious Diseases, Southwest Hospital Third Military Medical University(Army Medical University), Chongqing 400038, China.
Southwest Hospital · CNArmy Medical University · CN

Funding

Natural Science Foundation of China 81500479Program of Technology Innovation of Major Topics of First Affiliated Hospital, Third Military Medical University SWH2016ZDCX3022, SWH2016ZDCX3009
6 · The paper itself

Abstract

Alpha-1 antitrypsin deficiency is an autosomal codominant genetic disease characterized by low levels of alpha-1 antitrypsin in the blood. Clinically, in young patients, it mainly manifests as emphysema, acute/chronic liver injury and liver cancer. The treatment methods include symptomatic treatment and alpha -1 antitrypsin supplementation. However, the existing treatment cannot prevent the liver fibrosis progression. At present, more than ten cases of the disease have been reported in China, but the understanding of this disease is still indecisive. Moreover, there exists no biotherapy drug for this disorder. This article introduces the research progress of hepatocyte transplantation treatment for this disorder.

Indexed as

alpha 1-Antitrypsin DeficiencyPulmonary EmphysemaChinaHepatocytesHumansLiver CirrhosisCell transplantationHepatocyteStem cellα-1 antitrypsin deficiency

Identifiers

PMID33256287
PMCPMC12770059
OpenAlexW3108673604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.