Evidence map›Paper›PMID 33256224›Full record

ArticleNutrients2020

Functionally Relevant Differences in Plasma Fatty Acid Composition and Expression of Cytotoxic and Inhibitory NK Cell Receptors between Healthy Young and Healthy Elder Adults.

Juan Bautista De Sanctis, Daciana Catalina Dumut, Danuta Radzioch, Marián Hajdúch

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Juan Bautista De SanctisInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Hněvotínská 1333/5, 779 00 Olomouc, Czech Republic.
Daciana Catalina DumutDepartment of Experimental Medicine and McGill University, 1001 DeCarie Boulevard EM 23242, Montreal, QC H4A 3J1, Canada.
Danuta RadziochThe Research Institute of the McGill University Health Centre, Infectious Diseases and Immunity in the Global Health Program, 1001 DeCarie Boulevard EM 23242, Montreal, QC H4A 3J1, Canada.
Marián HajdúchInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Hněvotínská 1333/5, 779 00 Olomouc, Czech Republic.
Institute of Molecular and Translational Medicine · CZMcGill University Health Centre · CA

Funding

undefined <span style="color:gray;font-size:10px;">undefined</span> . CZ.02.1.01/0.0/0.0/16_019/0000868
6 · The paper itself

Abstract

(1) Background: In the healthy ageing, NK cell number is not modified; however, their spontaneous cytotoxicity decreases. We postulated that the age-dependent decline in metabolic activities might be responsible for this effect. (2) Methods: The fatty acid profile of 30 healthy young males (23 ± 4 years old, BMI 22.1 ± 1.3) and 30 older males (63 ± 5 years old, BMI 22.9 ± 2.5) donors were evaluated along with the expression of killing (KR) and inhibitory NK receptors (KIR) at basal level and after cultivation with fatty acids for 24 h. (3) Results: Significantly higher levels of oleic (

Indexed as

AdultAge FactorsCytotoxicity, ImmunologicFatty AcidsHumansMaleMiddle AgedReceptors, Natural Killer CellReference ValuesYoung AdultFatty AcidsReceptors, Natural Killer Cellageingkilling activating receptorskilling inhibitory receptors (KIR)natural killer cellssaturated fatty acidsunsaturated fatty acids

Identifiers

PMID33256224
PMCPMC7759996
OpenAlexW3107698167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.