Evidence map›Paper›PMID 33256176›Full record

ArticleJournal of clinical medicine2020

MRI Characteristics Accurately Predict Biochemical Recurrence after Radical Prostatectomy.

Cécile Manceau, Jean-Baptiste Beauval, Marine Lesourd, Christophe Almeras, Richard Aziza, Jean-Romain Gautier, Guillaume Loison, Ambroise Salin, Christophe Tollon, Michel Soulié and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Cécile ManceauDepartment of Urology, CHU Toulouse-IUCT Oncopole, 31400 Toulouse, France.
Jean-Baptiste BeauvalDepartment of Urology, La Croix du Sud Hospital, 31130 Quint Fonsegrives, France.
Marine LesourdDepartment of Urology, CHU Toulouse-IUCT Oncopole, 31400 Toulouse, France.ORCID 0000-0001-6001-1391
Christophe AlmerasDepartment of Urology, La Croix du Sud Hospital, 31130 Quint Fonsegrives, France.ORCID 0000-0002-1658-9177
Richard AzizaDepartment of Radiology, Institut Universitaire du Cancer Toulouse Oncopole, 31400 Toulouse, France.
Jean-Romain GautierDepartment of Urology, La Croix du Sud Hospital, 31130 Quint Fonsegrives, France.
Guillaume LoisonDepartment of Urology, La Croix du Sud Hospital, 31130 Quint Fonsegrives, France.
Ambroise SalinDepartment of Urology, La Croix du Sud Hospital, 31130 Quint Fonsegrives, France.
Christophe TollonDepartment of Urology, La Croix du Sud Hospital, 31130 Quint Fonsegrives, France.
Michel SouliéDepartment of Urology, CHU Toulouse-IUCT Oncopole, 31400 Toulouse, France.
Bernard MalavaudDepartment of Urology, CHU Toulouse-IUCT Oncopole, 31400 Toulouse, France.ORCID 0000-0003-2793-9459
Mathieu RoumiguiéDepartment of Urology, CHU Toulouse-IUCT Oncopole, 31400 Toulouse, France.ORCID 0000-0002-2412-146X
Guillaume PloussardDepartment of Urology, La Croix du Sud Hospital, 31130 Quint Fonsegrives, France.ORCID 0000-0002-6004-2152
Lyon Genou Centre Albert Trillat · FRInstitut universitaire du cancer de Toulouse Oncopole · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter radical prostatectomy (RP), biochemical recurrence (BCR) is associated with an increased risk of developing distant metastasis and prostate cancer specific and overall mortality.

methodsThe two-centre study included 521 consecutive patients undergoing RP for positive pre-biopsy magnetic resonance imaging (MRI) and pathologically proven prostate cancer (PCa), after which a combination scheme of fusion-targeted biopsy (TB) and systematic biopsy was performed. We assessed correlations between MRI characteristics, International Society of Urological Pathology (ISUP) grade group in TB, and outcomes after RP. We developed an imaging-based risk classification for improving BCR prediction.

resultsHigher Prostate Imaging and Reporting and Data System (PI-RADS) score (

conclusionsIn this cohort, PI-RADS score, MRI stage, and ISUP grade group in MRI-TB were significantly predictive for disease features and recurrence after RP. Imaging-based risk classification integrating these three factors competed with d'Amico classification for predicting BCR.

Indexed as

biochemical recurrenceimaging-based risk classificationmagnetic resonance imaging (MRI)prostate cancerprostate cancer prognosisradical prostatectomysystematic biopsiestargeted biopsies

Identifiers

PMID33256176
PMCPMC7760513
OpenAlexW3108520272

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.