Evidence map›Paper›PMID 33256173›Full record

ArticleMicroorganisms2020

Comparative Metagenomics of Palearctic and Neotropical Avian Cloacal Viromes Reveal Geographic Bias in Virus Discovery.

Daniel A Truchado, Alejandro Llanos-Garrido, David A Oropesa-Olmedo, Belén Cerrada, Pablo Cea, Michaël A J Moens, Esperanza Gomez-Lucia, Ana Doménech, Borja Milá, Javier Pérez-Tris and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Daniel A TruchadoDepartment of Genetics, Physiology and Microbiology, Faculty of Biology, Complutense University of Madrid, José Antonio Novais, 12, 28040 Madrid, Spain.ORCID 0000-0003-0448-0112
Alejandro Llanos-GarridoDepartment of Organismic and Evolutionary Biology, Faculty of Arts & Sciences, Harvard University, 38 Oxford St, Cambridge, MA 02138, USA.
David A Oropesa-OlmedoDepartment of Genetics, Physiology and Microbiology, Faculty of Biology, Complutense University of Madrid, José Antonio Novais, 12, 28040 Madrid, Spain.
Belén CerradaDepartment of Genetics, Physiology and Microbiology, Faculty of Biology, Complutense University of Madrid, José Antonio Novais, 12, 28040 Madrid, Spain.
Pablo CeaDepartment of Genetics, Physiology and Microbiology, Faculty of Biology, Complutense University of Madrid, José Antonio Novais, 12, 28040 Madrid, Spain.
Michaël A J MoensFundación de Conservación Jocotoco, Lizardo García E9-104 y Andrés Xaura, Quito 170143, Ecuador.
Esperanza Gomez-LuciaDepartment of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Avda. Puerta de Hierro s/n, 28040 Madrid, Spain.ORCID 0000-0002-5261-0586
Ana DoménechDepartment of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Avda. Puerta de Hierro s/n, 28040 Madrid, Spain.ORCID 0000-0001-8074-7857
Borja MiláNational Museum of Natural Sciences, Spanish National Research Council (CSIC), 28006 Madrid, Spain.
Javier Pérez-TrisDepartment of Biodiversity, Ecology and Evolution, Faculty of Biology, Complutense University of Madrid, José Antonio Novais, 12, 28040 Madrid, Spain.ORCID 0000-0001-5535-3100
Daniel CadarBernhard Nocht Institute for Tropical Medicine, WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research, National Reference Centre for Tropical Infectious Diseases, 20359 Hamburg, Germany.ORCID 0000-0002-8063-2766
Laura BenítezDepartment of Genetics, Physiology and Microbiology, Faculty of Biology, Complutense University of Madrid, José Antonio Novais, 12, 28040 Madrid, Spain.ORCID 0000-0001-9737-3572
Universidad Complutense de Madrid · ESBernhard Nocht Institute for Tropical Medicine · DEConocoPhillips (United States) · USConsejo Superior de Investigaciones Científicas · ESHarvard University · US

Funding

ANR CEBA2015-TROCSYMBANR CEBA:ANR-10-LABX-25-01Complutense University of Madrid CT27/16-CT28/16Spanish National Research Agency CGL2013-41642-P/BOSSpanish National Research Agency CGL2017-82117-P
6 · The paper itself

Abstract

Our understanding about viruses carried by wild animals is still scarce. The viral diversity of wildlife may be best described with discovery-driven approaches to the study of viral diversity that broaden research efforts towards non-canonical hosts and remote geographic regions. Birds have been key organisms in the transmission of viruses causing important diseases, and wild birds are threatened by viral spillovers associated with human activities. However, our knowledge of the avian virome may be biased towards poultry and highly pathogenic diseases. We describe and compare the fecal virome of two passerine-dominated bird assemblages sampled in a remote Neotropical rainforest in French Guiana (Nouragues Natural Reserve) and a Mediterranean forest in central Spain (La Herrería). We used metagenomic data to quantify the degree of functional and genetic novelty of viruses recovered by examining if the similarity of the contigs we obtained to reference sequences differed between both locations. In general, contigs from Nouragues were significantly less similar to viruses in databases than contigs from La Herrería using Blastn but not for Blastx, suggesting that pristine regions harbor a yet unknown viral diversity with genetically more singular viruses than more studied areas. Additionally, we describe putative novel viruses of the families

Indexed as

animal virusesavian viromebiodiscoveryNeotropical birdsremote areaswildlife virome

Identifiers

PMID33256173
PMCPMC7761369
OpenAlexW3106544167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.