Evidence map›Paper›PMID 33256166›Full record

ArticleInternational journal of molecular sciences2020

Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2.

Rania Hamdy, Samia A Elseginy, Noha I Ziedan, Mohamed El-Sadek, Elsaid Lashin, Arwyn T Jones, Andrew D Westwell

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Editorial for Special Issue "Bioactive Oxadiazoles".International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Rania HamdySchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, Wales, UK.
Samia A ElseginySchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, Wales, UK.ORCID 0000-0002-0040-0288
Noha I ZiedanSchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, Wales, UK.
Mohamed El-SadekFaculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0002-6038-1496
Elsaid LashinFaculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Arwyn T JonesSchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, Wales, UK.ORCID 0000-0003-2781-8905
Andrew D WestwellSchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, Wales, UK.ORCID 0000-0002-5166-9236
Zagazig University · EGCardiff University · GBUniversity of Bristol · GBUniversity of Chester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 2-(1

Indexed as

Drug DesignAntineoplastic AgentsBinding SitesCell Line, TumorCell ProliferationHumansInhibitory Concentration 50Models, MolecularOxadiazolesProtein BindingProto-Oncogene Proteins c-bcl-2Antineoplastic AgentsOxadiazolesProto-Oncogene Proteins c-bcl-2anticancerapoptosisaromatic heterocycleBcl-2 inhibitorchemical synthesisindolemolecular modelingoxadiazole

Identifiers

PMID33256166
PMCPMC7730549
OpenAlexW3107563503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.