Evidence map›Paper›PMID 33256145›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Redox-Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy.

Cristina Valentim-Coelho, Fátima Vaz, Marília Antunes, Sofia Neves, Inês L Martins, Hugo Osório, Amélia Feliciano, Paula Pinto, Cristina Bárbara, Deborah Penque

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Cristina Valentim-CoelhoLaboratório de Proteómica, Departamento de Genética Humana, Instituto Nacional de Saúde Dr. Ricardo Jorge, 1649-016 Lisboa, Portugal.
Fátima VazLaboratório de Proteómica, Departamento de Genética Humana, Instituto Nacional de Saúde Dr. Ricardo Jorge, 1649-016 Lisboa, Portugal.
Marília AntunesCentro de Estatística e Aplicações da Universidade de Lisboa e Departamento de Estatística e Investigação Operacional, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.ORCID 0000-0002-1257-2829
Sofia NevesLaboratório de Proteómica, Departamento de Genética Humana, Instituto Nacional de Saúde Dr. Ricardo Jorge, 1649-016 Lisboa, Portugal.
Inês L MartinsLaboratório de Proteómica, Departamento de Genética Humana, Instituto Nacional de Saúde Dr. Ricardo Jorge, 1649-016 Lisboa, Portugal.
Hugo Osórioi3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-6362-8255
Amélia FelicianoServiço de Pneumologia, Centro Hospitalar Lisboa Norte-CHLN, 1649-035 Lisboa, Portugal.
Paula PintoServiço de Pneumologia, Centro Hospitalar Lisboa Norte-CHLN, 1649-035 Lisboa, Portugal.
Cristina BárbaraServiço de Pneumologia, Centro Hospitalar Lisboa Norte-CHLN, 1649-035 Lisboa, Portugal.ORCID 0000-0003-0915-4105
Deborah PenqueLaboratório de Proteómica, Departamento de Genética Humana, Instituto Nacional de Saúde Dr. Ricardo Jorge, 1649-016 Lisboa, Portugal.ORCID 0000-0002-4527-7148
National Institute of Health Dr. Ricardo Jorge · PTUniversity of Lisbon · PTCentro Hospitalar Lisboa Norte · PTUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we examined the effect of six months of positive airway pressure (PAP) therapy on Obstructive Sleep Apnea (OSA) red blood cell (RBC) proteome by two dimensional difference gel electrophoresis (2D-DIGE) - based proteomics followed by Western blotting (WB) validation. The discovered dysregulated proteins/proteoforms are associated with cell death, H

Indexed as

Cys-sulfinylation/Cys-sulfonylationglyceraldehyde-3-phosphate dehydrogenase (GAPDH)obstructive sleep apnea (OSA)peroxiredoxin-2 (PRDX2)positive airway pressure (PAP)proteomics-biomarkers

Identifiers

PMID33256145
PMCPMC7761104
OpenAlexW3106990567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.