Evidence map›Paper›PMID 33256137›Full record

ArticleInternational journal of molecular sciences2020

Lung Regulatory T Cells Express Adiponectin Receptor 1: Modulation by Obesity and Airway Allergic Inflammation.

Patricia Ramos-Ramírez, Carina Malmhäll, Kristina Johansson, Mikael Adner, Jan Lötvall, Apostolos Bossios

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Serum leptin and adiponectin function as indicators of allergic sensitization in pediatric adenotonsillar hypertrophy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Adipose Tissue Inflammation and Pulmonary Dysfunction in Obesity.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Adiponectin and Asthma: Knowns, Unknowns and Controversies.International journal of molecular sciences · 2021
    Review
  11. Review
  12. Article
  13. TGF-β: The missing link in obesity-associated airway diseases?Current research in pharmacology and drug discovery · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Patricia Ramos-RamírezKrefting Research Centre, Department for Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.ORCID 0000-0001-5546-277X
Carina MalmhällKrefting Research Centre, Department for Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.ORCID 0000-0001-6696-7570
Kristina JohanssonKrefting Research Centre, Department for Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.
Mikael AdnerInstitute of Environmental Medicine, Karolinska Institutet, SE-171 65 Stockholm, Sweden.
Jan LötvallKrefting Research Centre, Department for Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.ORCID 0000-0001-9195-9249
Apostolos BossiosKrefting Research Centre, Department for Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.ORCID 0000-0002-0494-2690
University of Gothenburg · SEKarolinska Institutet · SEKarolinska University Hospital · SE

Funding

P.R.R. was supported by CONACyT, Mexico 232150 / 261200Swedish Heart Lung Foundation 20120565, 20170747, 20180219, 20180220
6 · The paper itself

Abstract

Regulatory T cells (Tregs) decrease in the adipose tissue upon weight gain, contributing to persistent low-grade inflammation in obesity. We previously showed that adipose tissue Tregs express the adiponectin receptor 1 (AdipoR1); however, the expression in lung Tregs is still unknown. Here, we aimed to determine whether Helios

Indexed as

Adipose TissueAnimalsBody WeightDiet, High-FatDNA-Binding ProteinsEosinophiliaEosinophilsForkhead Transcription FactorsHypersensitivityInflammationLungMaleMice, Inbred C57BLMice, ObeseReceptors, AdiponectinT-Lymphocytes, RegulatoryDNA-Binding ProteinsForkhead Transcription FactorsFoxp3 protein, mouseReceptors, AdiponectinTranscription FactorsZfpn1a2 protein, mouseAdipoR1adipose tissueallergic inflammationDIO-mouse modelHelioslungobesityobesity-related asthmaregulatory T cells

Identifiers

PMID33256137
PMCPMC7730828
OpenAlexW3109177834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.