Evidence map›Paper›PMID 33256114›Full record

ArticleNutrients2020

Effects of High and Low Protein Diets on Inflammatory Profiles in People with Morbid Obesity: A 3-Week Intervention Study.

Liselot Koelman, Mariya Markova, Nicole Seebeck, Silke Hornemann, Anke Rosenthal, Volker Lange, Olga Pivovarova-Ramich, Krasimira Aleksandrova

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Impact of Dietary Fiber on Inflammation in Humans.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Liselot KoelmanSenior Scientist Group Nutrition, Immunity and Metabolism, Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.
Mariya MarkovaDepartment of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.
Nicole SeebeckInstitute of Nutritional Science, University of Potsdam, 14558 Nuthetal, Germany.
Silke HornemannDepartment of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.
Anke RosenthalClinic for Nutritional Medicine, 10625 Berlin, Germany.
Volker LangeCenter for Obesity and Metabolic Surgery, Vivantes Hospital, 13585 Berlin, Germany.
Olga Pivovarova-RamichDepartment of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.ORCID 0000-0002-3583-8546
Krasimira AleksandrovaSenior Scientist Group Nutrition, Immunity and Metabolism, Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.
Deutsches Diabetes-Zentrum e.V. · DEUniversity of Potsdam · DEVivantes Klinikum · DE

Funding

Deutsche Zentrum für Diabetesforschung Is FGF21 as novel bidirectional regulator of protein preference and aversion: regulatory mechanisms and clinical implicationsDeutsche Zentrum für Diabetesforschung Role of Wnt-inducible signaling pathway protein-1 (WISP-1) in adipose tissue and liver fibrosis in mice and menEuropean Association for the Study of Diabetes Identification of individual response criteria for reduction of hepatic fat by nutritional approaches and subsequent maintenance by dietary strategies
6 · The paper itself

Abstract

Nutritional interventions in morbidly obese individuals that effectively reverse a pro-inflammatory state and prevent obesity-associated medical complications are highly warranted. Our aim was to evaluate the effect of high (HP) or low (LP) protein diets on circulating immune-inflammatory biomarkers, including C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-a), interleukin-10 (IL-10), monocyte chemoattractant protein-1 (MCP-1), chemerin, omentin, leptin, total adiponectin, high molecular weight adiponectin, and fetuin-A. With this aim, 18 people with morbid obesity were matched into two hypocaloric groups: HP (30E% protein,

Indexed as

AdiponectinAdultBiomarkersChemokine CCL2ChemokinesC-Reactive ProteinCytokinesDietary ProteinsDiet, High-ProteinDiet, Protein-RestrictedFemaleGPI-Linked ProteinsHumansInflammationInterleukin-10Interleukin-6AdiponectinBiomarkersChemokine CCL2ChemokinesC-Reactive ProteinCytokinesDietary ProteinsGPI-Linked ProteinsInterleukin-10Interleukin-6ITLN1 protein, humanLectinsLeptinRARRES2 protein, humanTumor Necrosis Factor-alphahigh proteininflammatory biomarkerslow proteinmorbid obesitynutritional intervention

Identifiers

PMID33256114
PMCPMC7759799
OpenAlexW3106898574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.