Evidence map›Paper›PMID 33255850›Full record

ArticleJournal of clinical medicine2020

Immortalization of Salivary Gland Epithelial Cells of Xerostomic Patients: Establishment and Characterization of Novel Cell Lines.

Braxton D Noll, Alexandre Grdzelishvili, Michael T Brennan, Farah Bahrani Mougeot, Jean-Luc C Mougeot

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Special Issue-"Diseases of the Salivary Glands".Journal of clinical medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Braxton D NollCarolinas Medical Center-Atrium Health, Charlotte, NC 28203, USA.
Alexandre GrdzelishviliCarolinas Medical Center-Atrium Health, Charlotte, NC 28203, USA.
Michael T BrennanCarolinas Medical Center-Atrium Health, Charlotte, NC 28203, USA.ORCID 0000-0003-0638-4335
Farah Bahrani MougeotCarolinas Medical Center-Atrium Health, Charlotte, NC 28203, USA.
Jean-Luc C MougeotCarolinas Medical Center-Atrium Health, Charlotte, NC 28203, USA.
Carolinas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary Sjögren's Syndrome (pSS) is an autoimmune disease mainly affecting salivary and lacrimal glands. Previous pSS studies have relied on primary cell culture models or cancer cell lines with limited relevance to the disease. Our objective was to generate and characterize immortalized salivary gland epithelial cells (iSGECs) derived from labial salivary gland (LSG) biopsies of pSS patients (focus score > 1) and non-Sjögren's Syndrome (nSS) xerostomic (i.e., sicca) female patients. To characterize iSGECs (

Indexed as

acinarductalimmortalizationsalivary glandSGECSjögren’s syndromespheroidxerostomia

Identifiers

PMID33255850
PMCPMC7768371
OpenAlexW3106912210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.