Evidence map›Paper›PMID 33255826›Full record

ReviewInternational journal of molecular sciences2020

Role of microRNA and Oxidative Stress in Influenza A Virus Pathogenesis.

Md Mamunul Haque, Dhiraj P Murale, Jun-Seok Lee

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Pathomechanism of Fever-Induced Liver Failure in NBAS Deficiency and Treatment Effect of NAC-Observations In Vitro and In Vivo.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  4. Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. miRNA in Molecular Diagnostics.Bioengineering (Basel, Switzerland) · 2022
    Review
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Md Mamunul HaqueMolecular Recognition Research Center, Korea Institute of Science and Technology (KIST), Seoul 02792, Korea.ORCID 0000-0002-3494-4953
Dhiraj P MuraleMolecular Recognition Research Center, Korea Institute of Science and Technology (KIST), Seoul 02792, Korea.
Jun-Seok LeeMolecular Recognition Research Center, Korea Institute of Science and Technology (KIST), Seoul 02792, Korea.ORCID 0000-0003-3641-1728
Korea Institute of Science and Technology · KRBio-Medical Science (South Korea) · KR

Funding

Ministry of Science and ICT, South Korea NRF-2018H1D3A1A02074556Ministry of Science and ICT, South Korea NRF-2018M3A9H4079286Ministry of Science and ICT, South Korea NRF-2020R1A2C2004422
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are non-coding RNAs that regulate diverse cellular pathways by controlling gene expression. Increasing evidence has revealed their critical involvement in influenza A virus (IAV) pathogenesis. Host-IAV interactions induce different levels of oxidative stress (OS) by disrupting the balance between reactive oxygen species (ROS) and antioxidant factors. It is thought that miRNA may regulate the expression of ROS; conversely, ROS can induce or suppress miRNA expression during IAV infection. Thus, miRNA and OS are the two key factors of IAV infection and pathogenesis. Accordingly, interactions between OS and miRNA during IAV infection might be a critical area for further research. In this review, we discuss the crosstalk between miRNAs and OS during IAV infection. Additionally, we highlight the potential of miRNAs as diagnostic markers and therapeutic targets for IAV infections. This knowledge will help us to study host-virus interactions with novel intervention strategies.

Indexed as

Gene Expression RegulationHumansImmunity, InnateInfluenza A virusInfluenza, HumanMicroRNAsOxidative StressReactive Oxygen SpeciesVirus ReplicationMicroRNAsReactive Oxygen Speciesinfluenza A virusmicroRNAoxidative stress

Identifiers

PMID33255826
PMCPMC7728370
OpenAlexW3108673498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.