Evidence map›Paper›PMID 33255782›Full record

ReviewMolecules (Basel, Switzerland)2020

Biotransformation of Oleanane and Ursane Triterpenic Acids.

Natalia A Luchnikova, Victoria V Grishko, Irina B Ivshina

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Microbiology · 2023
    Article
  5. Article
  6. Article
  7. Biocatalysis in the Chemistry of Lupane Triterpenoids.Molecules (Basel, Switzerland) · 2021
    Review
  8. Review
  9. Microbial Transformation ofFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Natalia A LuchnikovaInstitute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Ural Branch of the Russian Academy of Sciences, 614081 Perm, Russia.ORCID 0000-0002-9292-5726
Victoria V GrishkoInstitute of Technical Chemistry, Perm Federal Research Center, Ural Branch of the Russian Academy of Sciences, 614013 Perm, Russia.
Irina B IvshinaInstitute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Ural Branch of the Russian Academy of Sciences, 614081 Perm, Russia.ORCID 0000-0003-2558-4789

Funding

Ministry of Education and Science of the Russian Federation AAAA-A18-118030790037-7Ministry of Education and Science of the Russian Federation AAAA-A19-119112290008-4Ministry of Education and Science of the Russian Federation AAAA-A19-119112290010-7Russian Foundation for Basic Research 20-34-90104Russian Science Foundation 18-14-00140
6 · The paper itself

Abstract

Oleanane and ursane pentacyclic triterpenoids are secondary metabolites of plants found in various climatic zones and regions. This group of compounds is highly attractive due to their diverse biological properties and possible use as intermediates in the synthesis of new pharmacologically promising substances. By now, their antiviral, anti-inflammatory, antimicrobial, antitumor, and other activities have been confirmed. In the last decade, methods of microbial synthesis of these compounds and their further biotransformation using microorganisms are gaining much popularity. The present review provides clear evidence that industrial microbiology can be a promising way to obtain valuable pharmacologically active compounds in environmentally friendly conditions without processing huge amounts of plant biomass and using hazardous and expensive chemicals. This review summarizes data on distribution, microbial synthesis, and biological activities of native oleanane and ursane triterpenoids. Much emphasis is put on the processes of microbial transformation of selected oleanane and ursane pentacyclic triterpenoids and on the bioactivity assessment of the obtained derivatives.

Indexed as

BiotransformationBiosynthetic PathwaysFungiMolecular StructureOleanolic AcidPentacyclic TriterpenesPlantsTriterpenesoleananeOleanolic AcidPentacyclic TriterpenesTriterpenesursanebiological activitybiotransformationglycyrrhetinic acidoleanolic acidursolic acid

Identifiers

PMID33255782
PMCPMC7728323

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.