Evidence map›Paper›PMID 33255751›Full record

ReviewCancers2020

Recurrent Nasopharyngeal Cancer: Critical Review of Local Treatment Options Including Recommendations during the COVID-19 Pandemic.

Michaela Svajdova, Marian Sicak, Pavol Dubinsky, Marek Slavik, Pavel Slampa, Tomas Kazda

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. SEOM-TTCC clinical guideline for nasopharyngeal carcinoma (update 2025).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Guideline
  2. SEOM-TTCC clinical guideline in nasopharynx cancer (2021).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Guideline
  3. Pooled it
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Michaela SvajdovaDepartment of Radiation and Clinical Oncology, Central Military Hospital-Teaching Hospital Ruzomberok, 034 01 Ruzomberok, Slovakia.ORCID 0000-0002-6372-3295
Marian SicakDepartment of Otorhinolaryngology and Head and Neck Surgery, Central Military Hospital-Teaching Hospital, 034 01 Ruzomberok, Slovakia.
Pavol DubinskyDepartment of Radiation Oncology, East Slovakia Oncology Institute, 041 91 Kosice, Slovakia.
Marek SlavikDepartment of Radiation Oncology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
Pavel SlampaDepartment of Radiation Oncology, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic.
Tomas KazdaDepartment of Radiation Oncology, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic.ORCID 0000-0001-7288-8975
Masaryk Memorial Cancer Institute · CZMasaryk University · CZCatholic University in Ruzomberok · SKÚstredná Vojenská Nemocnica Ružomberok · SK

Funding

Ministry of Health, Czech Republic MMCI 00209805National Oncology Institute, Bratislava, Slovakia 20191111/SVKNOI/3
6 · The paper itself

Abstract

Recurrent nasopharyngeal carcinoma represents an extremely challenging therapeutic situation. Given the vulnerability of the already pretreated neurological structures surrounding the nasopharynx, any potential salvage retreatment option bears a significant risk of severe complications that result in high treatment-related morbidity, quality of life deterioration, and even mortality. Yet, with careful patient selection, long-term survival may be achieved after local retreatment in a subgroup of patients with local or regional relapse of nasopharyngeal cancer. Early detection of the recurrence represents the key to therapeutic success, and in the case of early stage disease, several curative treatment options can be offered to the patient, albeit with minimal support in prospective clinical data. In this article, an up-to-date review of published evidence on modern surgical and radiation therapy treatment options is summarized, including currently recommended treatment modifications of both therapeutic approaches during the coronavirus disease 2019 pandemic.

Indexed as

nasopharyngeal cancerrecurrencere-irradiationsalvage surgerytoxicity

Identifiers

PMID33255751
PMCPMC7760235
OpenAlexW3109262600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.