Evidence map›Paper›PMID 33255593›Full record

ReviewGenes2020

The Genetic Complexity of Prostate Cancer.

Eva Compérat, Gabriel Wasinger, André Oszwald, Renate Kain, Geraldine Cancel-Tassin, Olivier Cussenot

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Association of selectedPathology oncology research : POR · 2026
    Article
  3. Contemporary review of prognostic markers of prostate cancer from a pathologist perspective.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2025
    Review
  4. Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer.Virchows Archiv : an international journal of pathology · 2024
    Article
  5. The Transcriptomic Profiles ofInternational journal of molecular sciences · 2023
    Article
  6. Contribution of CD4+ T cell-mediated inflammation to diarrhea in patients with COVID-19.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Eva CompératCeRePP/GRC5 Predictive Onco-Urology, Sorbonne University, 75020 Paris, France.
Gabriel WasingerDepartment of Pathology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-0323-7180
André OszwaldDepartment of Pathology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-8298-6381
Renate KainDepartment of Pathology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-2428-543X
Geraldine Cancel-TassinCeRePP/GRC5 Predictive Onco-Urology, Sorbonne University, 75020 Paris, France.ORCID 0000-0002-9583-6382
Olivier CussenotCeRePP/GRC5 Predictive Onco-Urology, Sorbonne University, 75020 Paris, France.ORCID 0000-0002-9912-0533
Medical University of Vienna · ATSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is a major concern in public health, with many genetically distinct subsets. Genomic alterations in PCa are extraordinarily complex, and both germline and somatic mutations are of great importance in the development of this tumor. The aim of this review is to provide an overview of genetic changes that can occur in the development of PCa and their role in potential therapeutic approaches. Various pathways and mechanisms proposed to play major roles in PCa are described in detail to provide an overview of current knowledge.

Indexed as

GenomicsHumansMaleMutationProstatic NeoplasmsSignal Transductionandrogen receptorsERGgermline mutationsprostate cancerPTENsomatic mutationsTMPRSS2

Identifiers

PMID33255593
PMCPMC7760266
OpenAlexW3107133013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.