Evidence map›Paper›PMID 33255545›Full record

ArticleJournal of clinical medicine2020

Silver Sulfadiazine Eradicates Antibiotic-Tolerant

Enea Gino Di Domenico, Barbara De Angelis, Ilaria Cavallo, Francesca Sivori, Fabrizio Orlandi, Margarida Fernandes Lopes Morais D'Autilio, Chiara Di Segni, Pietro Gentile, Maria Giovanna Scioli, Augusto Orlandi and 12 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Silver sulfadiazine in modern dermatology.Dermatology online journal · 2025
    Review
  6. Article
  7. Review
  8. Skin microbiota and diabetic foot ulcers.Frontiers in microbiology · 2025
    Review
  9. Article
  10. Review
  11. Buruli Ulcer and Medical Geo-Microbiology.Infection and drug resistance · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 1 country.

Enea Gino Di DomenicoMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.ORCID 0000-0001-6295-6006
Barbara De AngelisDepartment of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, 00144 Rome, Italy.ORCID 0000-0003-1712-6702
Ilaria CavalloMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.
Francesca SivoriMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.
Fabrizio OrlandiDepartment of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, 00144 Rome, Italy.ORCID 0000-0001-8241-1812
Margarida Fernandes Lopes Morais D'AutilioDepartment of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, 00144 Rome, Italy.
Chiara Di SegniDepartment of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, 00144 Rome, Italy.
Pietro GentileDepartment of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, 00144 Rome, Italy.ORCID 0000-0003-3123-3977
Maria Giovanna ScioliDepartment of Anatomic Pathology, University of Rome Tor Vergata, 00144 Rome, Italy.
Augusto OrlandiDepartment of Anatomic Pathology, University of Rome Tor Vergata, 00144 Rome, Italy.ORCID 0000-0001-7202-5854
Giovanna D'AgostoMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.
Elisabetta TrentoMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.
Daniela KovacsCutaneous Physiopathology, San Gallicano Dermatological Institute, IRCCS, 00144 Rome, Italy.
Giorgia CardinaliCutaneous Physiopathology, San Gallicano Dermatological Institute, IRCCS, 00144 Rome, Italy.ORCID 0000-0002-7527-9451
Annunziata StefanileDepartment of Clinical Experimental Oncology, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Tatiana KoudriavtsevaDepartment of Clinical Experimental Oncology, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Grazia PrignanoMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.
Fulvia PimpinelliMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.
Ilaria Lesnoni La ParolaLichen Sclerosus Unit, Department of Dermatology, STI, Environmental Health, Tropical and Immigration, San Gallicano Dermatological Institute, IRCCS, 00144 Rome, Italy.
Luigi TomaDepartment of Research, Advanced Diagnostics, and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Valerio CervelliDepartment of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, 00144 Rome, Italy.
Fabrizio EnsoliMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.
San Gallicano Hospital · ITUniversity of Rome Tor Vergata · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections are among the most frequent and challenging events in diabetic foot ulcers (DFUs). Pathogenic bacteria growing in biofilms within host tissue are highly tolerant to environmental and chemical agents, including antibiotics. The present study was aimed at assessing the use of silver sulfadiazine (SSD) for wound healing and infection control in 16 patients with DFUs harboring biofilm-growing

Indexed as

biofilmchronic wounddiabetic foot ulcerPseudomonas aeruginosasilver sulfadiazineStaphylococcus aureus

Identifiers

PMID33255545
PMCPMC7760944
OpenAlexW3109904127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.