Evidence map›Paper›PMID 33255480›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Magnetic Nanoparticles with Dual Surface Functions-Efficient Carriers for Metalloporphyrin-Catalyzed Drug Metabolite Synthesis in Batch and Continuous-Flow Reactors.

Diána Balogh-Weiser, Balázs Decsi, Réka Krammer, Gergő Dargó, Ferenc Ender, János Mizsei, Róbert Berkecz, Benjámin Gyarmati, András Szilágyi, Róbert Tőtős and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Diána Balogh-WeiserDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary.ORCID 0000-0002-9957-1203
Balázs DecsiDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary.
Réka KrammerDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary.ORCID 0000-0001-9814-6347
Gergő DargóDepartment of Chemical and Environmental Process Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary.ORCID 0000-0002-1141-8379
Ferenc EnderDepartment of Electron Devices, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-111 Budapest, Hungary.
János MizseiDepartment of Electron Devices, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-111 Budapest, Hungary.ORCID 0000-0003-3411-1502
Róbert BerkeczInstitute of Pharmaceutical Analysis, Faculty of Pharmacy, University of Szeged, Somogyi utca 4., H-6720 Szeged, Hungary.
Benjámin GyarmatiDepartment of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary.
András SzilágyiDepartment of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary.
Róbert TőtősBiocatalysis and Biotransformation Research Center, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University of Cluj-Napoca, Arany János str. 11, 400028 Cluj-Napoca, Romania.
Csaba PaizsBiocatalysis and Biotransformation Research Center, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University of Cluj-Napoca, Arany János str. 11, 400028 Cluj-Napoca, Romania.
László PoppeDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary.ORCID 0000-0002-8358-1378
György T BaloghDepartment of Chemical and Environmental Process Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary.
Budapest University of Technology and Economics · HUBabeș-Bolyai University · ROUniversity of Szeged · HU

Funding

CPS4EU project in ECSEL Joint Undertaking 826276National Research, Development and Innovation Fund Thematic Excellence Program TUDFO/51757/2019-ITMNew National Excellence Programme of the Ministry of Innovation and Technology EFOP-3.6.1-16-2016-00008Romanian Ministry for European Funds NEMSyB, ID P37_273
6 · The paper itself

Abstract

The dual functionalization of magnetic nanoparticles with inert (methyl) and reactive (aminopropyl) groups enables efficient immobilization of synthetic metalloporphyrins (such as 5,10,15,20-tetrakis(2,3,4,5,6-pentafluorophenyl)iron(II) porphyrin and 5,10,15,20-tetrakis-(4-sulfonatophenyl)iron(II) porphyrin) via covalent or ionic interactions. The proportion of reactive function on the surface has significant effect on the biomimetic activity of metalloporphyrins. The optimized magnetic nanocatalyst containing porphyrin was successfully applied for biomimetic oxidation of antihypertensive drug Amlodipine in batch and continuous-flow reactors as well.

Indexed as

biomimetic oxidationdrug metabolismmagnetic nanoparticlesmetalloporphyrinmicrofluidic chip reactor

Identifiers

PMID33255480
PMCPMC7759782
OpenAlexW3107736259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.