Evidence map›Paper›PMID 33255283›Full record

ReviewMicroorganisms2020

Current Status and Future Strategies to Increase Secondary Metabolite Production from Cyanobacteria.

Yujin Jeong, Sang-Hyeok Cho, Hookeun Lee, Hyung-Kyoon Choi, Dong-Myung Kim, Choul-Gyun Lee, Suhyung Cho, Byung-Kwan Cho

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Chemodiversity and Biotechnological Potential of Microginins.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Growth of freshwater cyanobacteriumFrontiers in microbiology · 2023
    Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yujin JeongDepartment of Biological Sciences and KAIST Institutes for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0001-7466-9784
Sang-Hyeok ChoDepartment of Biological Sciences and KAIST Institutes for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0003-2668-4618
Hookeun LeeInstitute of Pharmaceutical Research, College of Pharmacy, Gachon University, Incheon 21999, Korea.ORCID 0000-0002-0696-8421
Hyung-Kyoon ChoiCollege of Pharmacy, Chung-Ang University, Seoul 06911, Korea.
Dong-Myung KimDepartment of Chemical Engineering and Applied Chemistry, Chungnam National University, Daejeon 34134, Korea.
Choul-Gyun LeeDepartment of Biological Engineering, Inha University, Incheon 22212, Korea.
Suhyung ChoDepartment of Biological Sciences and KAIST Institutes for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0002-4853-9617
Byung-Kwan ChoDepartment of Biological Sciences and KAIST Institutes for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Korea Advanced Institute of Science and Technology · KRGachon University · KRChungnam National University · KRInha University · KR

Funding

National Research Foundation of Korea NRF-2016M1A5A1027455National Research Foundation of Korea NRF-2016M1A5A1027458
6 · The paper itself

Abstract

Cyanobacteria, given their ability to produce various secondary metabolites utilizing solar energy and carbon dioxide, are a potential platform for sustainable production of biochemicals. Until now, conventional metabolic engineering approaches have been applied to various cyanobacterial species for enhanced production of industrially valued compounds, including secondary metabolites and non-natural biochemicals. However, the shortage of understanding of cyanobacterial metabolic and regulatory networks for atmospheric carbon fixation to biochemical production and the lack of available engineering tools limit the potential of cyanobacteria for industrial applications. Recently, to overcome the limitations, synthetic biology tools and systems biology approaches such as genome-scale modeling based on diverse omics data have been applied to cyanobacteria. This review covers the synthetic and systems biology approaches for advanced metabolic engineering of cyanobacteria.

Indexed as

cyanobacteriagenome-scale modelmetabolic engineeringphotosynthesissecondary metabolitessynthetic biologysystems biology

Identifiers

PMID33255283
PMCPMC7761380
OpenAlexW3107702438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.