Evidence map›Paper›PMID 33255148›Full record

ReviewInternational journal of molecular sciences2020

TRPV1 Channel: A Noxious Signal Transducer That Affects Mitochondrial Function.

Rebeca Juárez-Contreras, Karina Angélica Méndez-Reséndiz, Tamara Rosenbaum, Ricardo González-Ramírez, Sara Luz Morales-Lázaro

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  12. Utilization of Cannabidiol in Post-Organ-Transplant Care.International journal of molecular sciences · 2025
    Review
  13. Article
  14. Article
  15. Review
  16. Review
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  19. Article
  20. Membrane Interactivity of Capsaicin Antagonized by Capsazepine.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rebeca Juárez-ContrerasDepartment of Cognitive Neuroscience, Neurosciences Division, Institute of Cellular Physiology, National Autonomous University of Mexico, UNAM, Mexico City 04510, Mexico.
Karina Angélica Méndez-ReséndizDepartment of Cognitive Neuroscience, Neurosciences Division, Institute of Cellular Physiology, National Autonomous University of Mexico, UNAM, Mexico City 04510, Mexico.
Tamara RosenbaumDepartment of Cognitive Neuroscience, Neurosciences Division, Institute of Cellular Physiology, National Autonomous University of Mexico, UNAM, Mexico City 04510, Mexico.ORCID 0000-0002-4791-3195
Ricardo González-RamírezDepartment of Molecular Biology and Histocompatibility, "Dr. Manuel Gea González" General Hospital, Mexico City 14080, Mexico.ORCID 0000-0003-1399-8036
Sara Luz Morales-LázaroDepartment of Cognitive Neuroscience, Neurosciences Division, Institute of Cellular Physiology, National Autonomous University of Mexico, UNAM, Mexico City 04510, Mexico.
Universidad Nacional Autónoma de México · MXHospital General Dr. Manuel Gea Gonzalez · MX

Funding

Dirección General de Asuntos del Personal Académico (DGAPA)-Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica, PAPIIT IN206819
6 · The paper itself

Abstract

The Transient Receptor Vanilloid 1 (TRPV1) or capsaicin receptor is a nonselective cation channel, which is abundantly expressed in nociceptors. This channel is an important transducer of several noxious stimuli, having a pivotal role in pain development. Several TRPV1 studies have focused on understanding its structure and function, as well as on the identification of compounds that regulate its activity. The intracellular roles of these channels have also been explored, highlighting TRPV1's actions in the homeostasis of Ca

Indexed as

AnimalsCalciumCalcium SignalingHumansMitochondriaNociceptionPainSignal TransductionTRPV Cation ChannelsCalciumTRPV1 protein, humanTRPV Cation Channelsapoptosismitochondrial dysfunctionnociceptionpainROSTRPV1

Identifiers

PMID33255148
PMCPMC7734572
OpenAlexW3106808905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.