Evidence map›Paper›PMID 33253984›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2021

Influenza-Like Illness is Associated with Increased Short-Term Risk of Cervical Artery Dissection.

Madeleine D Hunter, Yeseon P Moon, Eliza C Miller, Erin R Kulick, Amelia K Boehme, Mitchell Sv Elkind

Open access · greenAbstract read
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Madeleine D HunterVagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA; Department of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA, USA. Electronic address: mdh2167@cumc.columbia.edu.
Yeseon P MoonDepartment of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA; Department of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA, USA. Electronic address: ypm2102@cumc.columbia.edu.
Eliza C MillerDepartment of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA; Department of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA, USA. Electronic address: ecm2137@cumc.columbia.edu.
Erin R KulickDepartment of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA; Department of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA, USA. Electronic address: erin.kulick@temple.edu.
Amelia K BoehmeDepartment of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA; Department of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, NY, USA. Electronic address: akb2188@cumc.columbia.edu.
Mitchell Sv ElkindDepartment of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA; Department of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, NY, USA. Electronic address: mse13@cumc.columbia.edu.
Columbia University · US

Funding

Neurovascular Unit Dysfunction in Women with Severe PreeclampsiaK23NS107645 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, ELIZA C · 2019 to 2023
$1.1M
NINDS NIH HHS K23 NS107645
6 · The paper itself

Abstract

introductionNon-traumatic Cervical Artery Dissection (CeAD) is a leading cause of ischemic stroke in the young. Influenza-like illnesses (ILI) trigger ischemic strokes. We hypothesized that influenza and ILI are associated with CeAD.

methodsIn a case-crossover study within the New York State (NYS) Department of Health Statewide Planning and Research Cooperative System (2006-2014), we used ICD-9 codes to exclude major trauma and to define CeAD, influenza, and the Centers for Disease Control defined ILI. We estimated the association of ILI and influenza with CeAD by comparing their prevalence in intervals immediately prior (0-30,0-90,0-180, and 0-365 days) to CeAD (case period) to their prevalence exactly one and two years earlier (control periods). Conditional logistic regression models generated odds ratios and 95% confidence intervals (OR, 95% CI). Models were adjusted for NYS estimates of influenza prevalence rates.

resultsOur sample included 3,610 cases of CeAD (mean age 52±16 years, 54.7% male, 6.2% Hispanic, 9.9% Black, 68.7% White). During case periods, 7.3% had one or more ILI. ILI was more likely within 90 days of CeAD compared to the same time interval one and two years before (0-15 days: adjusted OR 1.88, 95%CI 1.20-2.94; 0-30 days: adjusted OR 1.74, 95%CI 1.22-2.46; 0-90 days: adjusted OR 1.35, 95%CI 1.00-1.81). Influenza trended with CeAD (adjusted OR 1.86, 95%CI 0.37-9.24), but these results were not statistically significant, due to limited instances of confirmed influenza.

conclusionsILI may increase risk of CeAD for 15 days, and possibly up to three months.

Indexed as

AdultAgedCarotid Artery, Internal, DissectionCase-Control StudiesDatabases, FactualFemaleHumansInfluenza, HumanMaleMiddle AgedNew YorkPrevalenceRisk AssessmentRisk FactorsTime FactorsVertebral Artery DissectionCarotid artery dissectionCervical artery dissectionInfluenzaStrokeVertebral artery dissection

Identifiers

PMID33253984
PMCPMC10086675
OpenAlexW3107584462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.