ReviewRespiratory medicine2021
Tobacco use as a well-recognized cause of severe COVID-19 manifestations.
Review in Respiratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 64 citations in OpenAlex.
- Impact of the COVID-19 Pandemic on Changes in Tobacco Use Behavior: A Longitudinal Cohort Study in Japan.Journal of epidemiology · 2025Article
- Removal of Tobacco Specific Carcinogenic Nitrosamines in Mainstream Cigarette Smoke and Aqueous SolutionA Review.ACS omega · 2025Review
- Effects of COVID-19 Lockdowns on Alcohol Consumption, Hangovers and Smoking Among Young Adults (n = 140) in Germany: An On-Line Study.Human psychopharmacology · 2025Article
- COVID-19 Breakthrough Infection after Vaccination and Substance Use Disorders: A Longitudinal Cohort of People with and without HIV Receiving Care in the United States Veterans Health Administration.AIDS and behavior · 2024Article
- Association between sociodemographics and change in alcohol or tobacco use behaviors during the COVID-19 pandemic.PloS one · 2024Article
- Prevalence and association between alcohol, tobacco, and COVID-19: a study from a tribal predominant district in eastern India.Frontiers in public health · 2024Article
- Substances of abuse and their effect on SAR-CoV-2 pathogenesis.NeuroImmune pharmacology and therapeutics · 2023Review
- SARS-CoV-2 spike ectodomain targets α7 nicotinic acetylcholine receptors.The Journal of biological chemistry · 2023Article
- Patterns in Mental Health Symptomatology and Cigarette, E-cigarette, and Marijuana Use Among Texas Youth and Young Adults Amid the Coronavirus Disease 2019 Pandemic.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Article
- Increased healthcare costs in COVID-19 patients with unhealthy habits: The case of smoking.Tobacco induced diseases · 2023Article
- The Influence of Provaping "Gatewatchers" on the Dissemination of COVID-19 Misinformation on Twitter: Analysis of Twitter Discourse Regarding Nicotine and the COVID-19 Pandemic.Journal of medical Internet research · 2022Article
- Smoking cessation among people with mental illness: A South African perspective.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022Article
- The association between tobacco use and COVID-19 in Qatar.Preventive medicine reports · 2022Article
- Article
- Assessment of Exclusive, Dual, and Polytobacco E-Cigarette Use and COVID-19 Outcomes Among College Students.American journal of health promotion : AJHP · 2022Article
- Concurrent use of e-cigarettes and cannabis and associated COVID-19 symptoms, testing, and diagnosis among student e-cigarette users at four U.S. Universities.Addictive behaviors · 2022Article
- Population vitamin D status might be related to COVID-19 mortality but not with infection rate in Africa: evidence from ecological analysis.The Pan African medical journal · 2022Article
- The Impact of Tobacco Use on COVID-19 Outcomes: A Systematic Review.Journal of smoking cessation · 2022Review
- Impacts of COVID-19 on cigarette use, smoking behaviors, and tobacco purchasing behaviors.Drug and alcohol dependence · 2021Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe Coronavirus disease (COVID-19) infection is caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) primarily affecting the lungs. All tobacco-related illnesses including asthma, chronic obstructive pulmonary disease (COPD), and coronary artery disease are known to reduce the lung capacity and impair the immune system of the body and can greatly influence the ability to fight the novel coronavirus. The purpose of this state-of-the-art literature review is to summarize the evidence of the association of tobacco use with the severity of the COVID-19 manifestations.
methodArticles describing the association of tobacco use with the severity of COVID-19 manifestations were searched on PubMed, MEDLINE, and Google. This review covers the relevant studies on the subject published from January 1, 2020 to September 10, 2020.
resultsTobacco use in all forms, whether smoking or chewing, is significantly associated with severe COVID-19 outcomes. Pre-existing comorbidities in tobacco users such as cardiovascular diseases, diabetes, respiratory diseases and hypertension were found to further aggravate the disease manifestations making the treatment of such COVID-19 patients more challenging due to their rapid clinical deterioration.
conclusionsCurrent review indicates that nicotine exposure is linked to cardiopulmonary vulnerability to COVID-19 and tobacco use can be a potential risk factor for not only getting the viral infection but also its severe manifestations. The current pandemic provides a teachable moment to break the cycle of nicotine addiction and accelerate national tobacco control programs to achieve a tobacco-free world.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.