Evidence map›Paper›PMID 33253786›Full record

ArticleJournal of pain and symptom management2021

Development of the Oncolo-GIST ("Giving Information Strategically & Transparently") Intervention Manual for Oncologist Skills Training in Advanced Cancer Prognostic Information Communication.

Andrew S Epstein, Sophia E Kakarala, Valerie F Reyna, Ashish Saxena, Paul K Maciejewski, Manish A Shah, Holly G Prigerson

Open access · greenAbstract read
In one paragraph

Article in Journal of pain and symptom management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Timing of prognostic discussions in people with advanced cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  2. Article
  3. Article
  4. Clinician perspectives on delivering primary and specialty palliative care in community oncology practices.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  5. Article
  6. You Get (offered) What You (can) Pay for: Explaining Disparities in End-of-Life Cancer Care.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  7. Understanding Prognosis: Discrepancy in Prognosis Estimates Between Patients With Cirrhosis and their Hepatologists.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Andrew S EpsteinMemorial Sloan Kettering Cancer Center, New York, New York, USA; Weill Cornell Medicine, New York, New York, USA. Electronic address: epsteina@mskcc.org.
Sophia E KakaralaWeill Cornell Medicine, New York, New York, USA.
Valerie F ReynaCornell University, Ithaca, New York, USA.
Ashish SaxenaWeill Cornell Medicine, New York, New York, USA.
Paul K MaciejewskiWeill Cornell Medicine, New York, New York, USA.
Manish A ShahWeill Cornell Medicine, New York, New York, USA.
Holly G PrigersonWeill Cornell Medicine, New York, New York, USA.
Cornell University · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Psychosocial Approaches to Better Understanding & End-Stage Cancer Care (PROTECT)R35CA197730 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Holly Gwen Prigerson · 2015 to 2026
$11.2M
Communicating the Gist of Prognosis: Giving Information Simply and Transparently ("GIST") in Advanced CancerR21NR018693 · NINR · WEILL MEDICAL COLL OF CORNELL UNIV · PI EPSTEIN, ANDREW, PRIGERSON, HOLLY GWEN · 2019 to 2020
$488k
NCI NIH HHS P30 CA008748NCI NIH HHS R35 CA197730NINR NIH HHS R21 NR018693
6 · The paper itself

Abstract

contextPatient prognostic understanding is improved by oncologists' discussions of life expectancy. Most patients deem it important to discuss prognosis with their oncologists, but a minority of cancer patients within months of death report that they had such a discussion with their oncologist.

objectivesTo query stakeholders about their perspectives on the clinical approach and utility of an Oncolo-GIST manualized communication intervention, designed to enhance oncologists' ability to convey the gist of prognostic information simply, clearly, and effectively in the setting of progressing solid tumors and limited life expectancy.

methodsWe obtained and analyzed feedback on the intervention from solid tumor oncology clinicians and bereaved family caregivers, soliciting opinions on the clinical approach taken in the videos, acceptability and likely impact of the instructions, and specific phrases recommended in the manual.

resultsTwenty stakeholders (9 clinicians, 11 caregivers) participated. All agreed that oncologists should broach prognosis with patients, balancing honesty and sensitivity. Participants also advocated for oncologists to involve interprofessional team members (e.g., nurses, social workers) when serious mental health concerns arose. After the research team's discussion of the stakeholder feedback, the manual was modified to include or exclude preferred language and approaches.

conclusionThe Oncolo-GIST intervention was characterized as simple and potentially effective at conveying prognoses to advanced cancer patients. Future research should determine if this approach to medical communication, which distills the essence of prognostic messages clearly and simply, is associated with improvements in patients' prognostic understanding.

Indexed as

Gastrointestinal Stromal TumorsNeoplasmsOncologistsCommunicationHumansMedical OncologyPhysician-Patient RelationsPrognosisadvanced cancerinformed consentpatient educationPrognostication

Identifiers

PMID33253786
PMCPMC8155099
OpenAlexW3107201262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.