Evidence map›Paper›PMID 33253656›Full record

ReviewActa tropica2021

One year update on the COVID-19 pandemic: Where are we now?

Sanjay Kumar Mishra, Timir Tripathi

Open access · greenAbstract readReview
In one paragraph

Review in Acta tropica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 2 syntheses or guidelines pooled it, 199 citations in OpenAlex.

  1. Pooled it
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  7. Ivermectin repurposing for COVID-19: pharmacological and bibliometric analysis.Naunyn-Schmiedeberg's archives of pharmacology · 2025
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sanjay Kumar MishraDepartment of Botany, Ewing Christian College, Prayagraj- 211003, Uttar Pradesh, India.
Timir TripathiMolecular and Structural Biophysics Laboratory, Department of Biochemistry, North-Eastern Hill University, Shillong 793022, Meghalaya, India. Electronic address: timir.tripathi@gmail.com.
North Eastern Hill University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We are living through an unprecedented crisis with the rapid spread of the new coronavirus disease (COVID-19) worldwide within a short time. The timely availability of thousands of SARS-CoV-2 genomes has enabled the scientific community to study the origin, structures, and pathogenesis of the virus. The pandemic has spurred research publication and resulted in an unprecedented number of therapeutic proposals. Because the development of new drugs is time consuming, several strategies, including drug repurposing and repositioning, are being tested to treat patients with COVID-19. Researchers have developed several potential vaccine candidates that have shown promise in phase II and III trials. As of 12 November 2020, 164 candidate vaccines are in preclinical evaluation, and 48 vaccines are in clinical evaluation, of which four have cleared phase III trials (Pfizer/BioNTech's BNT162b2, Moderna's mRNA-1273, University of Oxford & AstraZeneca's AZD1222, and Gamaleya's Sputnik V vaccine). Despite the acquisition of a vast body of scientific information, treatment depends only on the clinical management of the disease through supportive care. At the pandemic's 1-year mark, we summarize current information on SARS-CoV-2 origin and biology, and advances in the development of therapeutics. The updated information presented here provides a comprehensive report on the scientific progress made in the past year in understanding of SARS-CoV-2 biology and therapeutics.

Indexed as

Adenosine MonophosphateAlanineAmidesAnimalsAntiviral AgentsChloroquineClinical Trials as TopicCoronavirusCoronavirus InfectionsCOVID-19COVID-19 VaccinesDrug CombinationsDrug RepositioningGlucocorticoidsHumansHydroxychloroquineAdenosine MonophosphateAlanineAmidesAntiviral AgentsAshwagandhaChloroquineCOVID-19 VaccinesDrug CombinationsfavipiravirGlucocorticoidsHydroxychloroquineIndolesIvermectinLopinavirlopinavir-ritonavir drug combinationPlant ExtractsPyrazinesremdesivirRitonavirSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2SulfidesumifenovirCoronavirusCOVID-19Drug repurposingOutbreakPandemicPathogenesisSARS-CoV-2TherapeuticsVaccines

Identifiers

PMID33253656
PMCPMC7695590
OpenAlexW3110503905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.