Evidence map›Paper›PMID 33253514›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie2020

Thromboprophylaxis practice patterns and beliefs among physicians treating patients with abdominopelvic cancers at a Canadian centre.

Kristen McAlpine, Rodney Breau, Marc Carrier, Philippe Violette, Christopher Knee, Ilias Cagiannos, Christopher Morash, Luke Lavallée

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of surgery. Journal canadien de chirurgie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A survey of physician perception and practices regarding pharmacological thromboprophylaxis during chemotherapy for bladder cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Kristen McAlpineFrom the Division of Urology, University of Ottawa, Ottawa, Ont. (McAlpine, Breau, Knee, Cagiannos, Morash, Lavallée); the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. (Breau, Carrier, Knee, Cagiannos, Morash, Lavallée); the Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ont. (Carrier); and the Departments of Health Research Methods, Evidence, and Impact and of Surgery, McMaster University, Hamilton, Ont. (Violette).
Rodney BreauFrom the Division of Urology, University of Ottawa, Ottawa, Ont. (McAlpine, Breau, Knee, Cagiannos, Morash, Lavallée); the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. (Breau, Carrier, Knee, Cagiannos, Morash, Lavallée); the Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ont. (Carrier); and the Departments of Health Research Methods, Evidence, and Impact and of Surgery, McMaster University, Hamilton, Ont. (Violette).
Marc CarrierFrom the Division of Urology, University of Ottawa, Ottawa, Ont. (McAlpine, Breau, Knee, Cagiannos, Morash, Lavallée); the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. (Breau, Carrier, Knee, Cagiannos, Morash, Lavallée); the Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ont. (Carrier); and the Departments of Health Research Methods, Evidence, and Impact and of Surgery, McMaster University, Hamilton, Ont. (Violette).
Philippe VioletteFrom the Division of Urology, University of Ottawa, Ottawa, Ont. (McAlpine, Breau, Knee, Cagiannos, Morash, Lavallée); the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. (Breau, Carrier, Knee, Cagiannos, Morash, Lavallée); the Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ont. (Carrier); and the Departments of Health Research Methods, Evidence, and Impact and of Surgery, McMaster University, Hamilton, Ont. (Violette).
Christopher KneeFrom the Division of Urology, University of Ottawa, Ottawa, Ont. (McAlpine, Breau, Knee, Cagiannos, Morash, Lavallée); the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. (Breau, Carrier, Knee, Cagiannos, Morash, Lavallée); the Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ont. (Carrier); and the Departments of Health Research Methods, Evidence, and Impact and of Surgery, McMaster University, Hamilton, Ont. (Violette).
Ilias CagiannosFrom the Division of Urology, University of Ottawa, Ottawa, Ont. (McAlpine, Breau, Knee, Cagiannos, Morash, Lavallée); the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. (Breau, Carrier, Knee, Cagiannos, Morash, Lavallée); the Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ont. (Carrier); and the Departments of Health Research Methods, Evidence, and Impact and of Surgery, McMaster University, Hamilton, Ont. (Violette).
Christopher MorashFrom the Division of Urology, University of Ottawa, Ottawa, Ont. (McAlpine, Breau, Knee, Cagiannos, Morash, Lavallée); the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. (Breau, Carrier, Knee, Cagiannos, Morash, Lavallée); the Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ont. (Carrier); and the Departments of Health Research Methods, Evidence, and Impact and of Surgery, McMaster University, Hamilton, Ont. (Violette).
Luke LavalléeFrom the Division of Urology, University of Ottawa, Ottawa, Ont. (McAlpine, Breau, Knee, Cagiannos, Morash, Lavallée); the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. (Breau, Carrier, Knee, Cagiannos, Morash, Lavallée); the Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ont. (Carrier); and the Departments of Health Research Methods, Evidence, and Impact and of Surgery, McMaster University, Hamilton, Ont. (Violette).
Ottawa Hospital · CACarrier (United States) · USMcMaster University · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is inadequate high-quality evidence on thromboprophylaxis for patients undergoing surgery for abdominopelvic cancer. We surveyed physicians who treat patients with abdominopelvic cancer to determine current thromboprophylaxis practice patterns and to determine where research is needed. Methods: We created an online survey with questions on thromboprophylaxis topics, including type of thromboprophylaxis used, timing of initial thromboprophylaxis dose, use of thromboprophylaxis during chemotherapy, use of extended-duration thromboprophylaxis and areas for future research. The survey questions were reviewed by external content experts to ensure they were appropriate and relevant. Surgeons, thrombosis experts and medical oncologists who manage patients with abdominopelvic cancers at 1 large Canadian academic centre were invited to complete the survey between January and April 2019. Results: Of the 57 physicians invited, 42 (74%) completed the survey, including 27 surgeons (response rate 79%), 9 thrombosis experts (response rate 75%) and 6 medical oncologists (response rate 55%). Most surgeons (22 [82%]) reported using mechanical thromboprophylaxis, whereas only 1 thrombosis expert (11%) recommended mechanical thromboprophylaxis. There was substantial variability in the timing of the initial dose of thromboprophylaxis, with 9/10 urologists (90%) and all 7 general surgeons giving the first dose intraoperatively, and three-quarters of thoracic surgeons (3/4 [75%]), gynecologists (3/4 [75%]) and thrombosis experts (7/9 [78%]) starting thromboprophylaxis after surgery. All medical oncologists believed chemotherapy increases the risk of venous thromboembolism, but 4 (67%) reported that they do not routinely prescribe thromboprophylaxis owing to bleeding concerns. Most respondents (35/38 [92%]) felt there was a need for more research on thromboprophylaxis and indicated willingness to participate in future clinical trials. Conclusion: Variability exists in contemporary thromboprophylaxis practice patterns among physicians treating patients with abdominopelvic cancer. Future research is needed to standardize care and improve outcomes for patients.

Indexed as

Abdominal NeoplasmsAnticoagulantsCanadaHumansPelvic NeoplasmsPerioperative CarePostoperative ComplicationsPractice Guidelines as TopicPractice Patterns, Physicians'SurgeonsSurgical Procedures, OperativeSurveys and QuestionnairesVenous ThromboembolismAnticoagulants

Identifiers

PMID33253514
PMCPMC7747845
OpenAlexW3109774758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.