ArticleYonago acta medica2020
Hematological Parameters and Clinical Features in Patients with Advanced Chronic Kidney Disease.
Article in Yonago acta medica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Predictive Role of Hematological Biomarkers in Chronic Kidney Disease Progression.Journal of clinical laboratory analysis · 2026Article
- Predictive value of serum chitinase 3-like 1 for dysfunctional autogenous arteriovenous fistulas in patients with chronic kidney disease stage G5.Clinics (Sao Paulo, Brazil) · 2025Article
- Hematological Indices and Abnormalities in Chronic Kidney Disease and Their Associations With Disease Severity.Cureus · 2025Article
- Diagnostic value of neutrophil-to-lymphocyte ratio, fibrinogen-to-albumin ratio and red blood cell distribution width in tuberculosis combined with other bacterial infections.BMC pulmonary medicine · 2025Article
- Neutrophil-to-lymphocyte ratio as a novel predictor of sarcopenia in maintenance hemodialysis patients: a cross-sectional study exploring associations across body composition categories.BMC musculoskeletal disorders · 2025Article
- Article
- Mendelian randomization analysis revealed that albuminuria is the key factor affecting socioeconomic status in CKD patients.Renal failure · 2024Article
- Red blood cell distribution width at admission predicts outcome in critically ill patients with kidney failure: a retrospective cohort study based on the MIMIC-IV database.Renal failure · 2022Article
- Association of mean platelet volume/lymphocyte ratio with inflammation in non-dialysis patients with chronic kidney disease stages 1-4: A retrospective study.Frontiers in immunology · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHematological parameters like red cell distribution width (RDW) and mean platelet volume (MPV) were reported to be associated with inflammation, atherosclerosis, and chronic kidney disease (CKD) progression. In this study, we evaluated RDW and MPV along with clinical features in patients with advanced CKD. We also aimed to detect clues for causative relations concerning these parameters, renal function and comorbidities.
methodsStage 3-5 CKD patients (627 total) were included (mean age 63.1 years, 48.3% male). Patients with malignancies, cirrhosis, infections, severe anemia, and systemic inflammation were excluded. Patients were evaluated for clinical features and grouped for comparison using median RDW and MPV. Linear regression models were generated to predict potential influences on RDW and MPV.
resultsMean estimated glomerular filtration rate (eGFR) was 27.3 mL/min/1.73m
conclusionIn this study, we found that high RDW is associated with comorbidity burden, anemia, and inflammatory status in patients with advanced CKD. Meanwhile, low MPV seems to be associated with worse renal function.
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