ArticlePLoS neglected tropical diseases2020
Analyses of the performance of the Ebola virus disease alert management system in South Sudan: August 2018 to November 2019.
Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Role and effectiveness of telephone hotlines in outbreak response in Africa: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Resilience as recovery: stakeholder perspectives on Uganda's health system response to infectious disease shocks.Frontiers in health services · 2026Article
- Rapid response to hemorrhagic fever emergence in Guinea: community-based systems can enhance engagement and sustainability.PloS one · 2025Article
- Telephone hotlines for infectious disease outbreaks in Africa: A review and qualitative study.Journal of public health in Africa · 2024Article
- Sustainable strategies for Ebola virus disease outbreak preparedness in Africa: a case study on lessons learnt in countries neighbouring the Democratic Republic of the Congo.Infectious diseases of poverty · 2022Article
- Assessment of infection prevention and control readiness for Ebola virus and other diseases outbreaks in a humanitarian crisis setting: a cross-sectional study of health facilities in six high-risk States of South Sudan.The Pan African medical journal · 2022Article
- Evaluation of integrated disease surveillance and response (IDSR) and early warning and response network (EWARN) in South Sudan 2021.The Pan African medical journal · 2022Article
- South Sudan's road to universal health coverage: a slow but steady journey.The Pan African medical journal · 2022Article
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Authors and funding
20 authors at 3 institutions in 3 countries.
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Abstract
South Sudan implemented Ebola virus disease preparedness interventions aiming at preventing and rapidly containing any importation of the virus from the Democratic Republic of Congo starting from August 2018. One of these interventions was a surveillance system which included an Ebola alert management system. This study analyzed the performance of this system. A descriptive cross-sectional study of the Ebola virus disease alerts which were reported in South Sudan from August 2018 to November 2019 was conducted using both quantitative and qualitative methods. As of 30 November 2019, a total of 107 alerts had been detected in the country out of which 51 (47.7%) met the case definition and were investigated with blood samples collected for laboratory confirmation. Most (81%) of the investigated alerts were South Sudanese nationals. The alerts were identified by health workers (53.1%) at health facilities, at the community (20.4%) and by screeners at the points of entry (12.2%). Most of the investigated alerts were detected from the high-risk states of Gbudwe (46.9%), Jubek (16.3%) and Torit (10.2%). The investigated alerts commonly presented with fever, bleeding, headache and vomiting. The median timeliness for deployment of Rapid Response Team was less than one day and significantly different between the 6-month time periods (K-W = 7.7567; df = 2; p = 0.0024) from 2018 to 2019. Strengths of the alert management system included existence of a dedicated national alert hotline, case definition for alerts and rapid response teams while the weaknesses were occasional inability to access the alert toll-free hotline and lack of transport for deployment of the rapid response teams which often constrain quick response. This study demonstrates that the Ebola virus disease alert management system in South Sudan was fully functional despite the associated challenges and provides evidence to further improve Ebola preparedness in the country.
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