ReviewAnatolian journal of cardiology2020
A comprehensive review of the diagnosis and management of mitral paravalvular leakage.
Review in Anatolian journal of cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparing the Direct Oral Anticoagulants versus Vitamin K Antagonists in Bioprosthetic Valves: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisPooled it
- Transcatheter Closure of Paravalvular Leaks: Efficacy, Techniques, and Outcomes From a Single-Center Prospective Study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Amplatzer-Based Transcatheter Paravalvular Leak Closure: A Narrative Review of Device Design, Procedural Strategy, Safety, and Outcomes.Life (Basel, Switzerland) · 2026Review
- Pathophysiology, diagnosis, and management of hemolysis in patients with prosthetic valve related paravalvular leaks.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026Review
- Transcatheter Paravalvular Leak Closure: A Step-by-Step Guide.Journal of cardiovascular development and disease · 2026Review
- Schematic Clock Diagram to Assess Mitral Paravalvular Leak by 2D TEE.Annals of cardiac anaesthesia · 2025Article
- Complications of transcatheter paravalvular leak device closure of mitral valve: An updated review of the literature and a rare case presentation.Clinical cardiology · 2024Review
- Transcatheter Closure or Surgery for Symptomatic Paravalvular Leaks: The Multicenter KISS Registry.Journal of the American Heart Association · 2024Article
- Article
- Percutaneous Management of Bioprosthetic Mitral Valve Dehiscence with Combined Valve-in-Valve Replacement and Paravalvular Leak Closure.Methodist DeBakey cardiovascular journal · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitral paravalvular leaks (PVLs) commonly occur in patients with prosthetic valves. Paravalvular defects may be clinically inconsequential and may aggravate hemolysis or cause heart failure through regurgitation. Accordingly, patients may eventually require intervention such as redo surgery or a transcatheter closure of the defects. The introduction of purpose-specific closure devices and new steerable catheters has opened a new frontier for the transcatheter PVL closure. This mode of treatment is an initial therapy in most centers with experienced structural heart team. However, head-to-head data comparing two treatment modalities (surgery and transcatheter closure) are limited, and the world-wide experience is based on nonrandomized studies. Multimodality imaging, including three-dimensional transesophageal echocardiography, facilitates the delineation of mitral PVLs and provides essential data that aids the communication between the members of the structural heart team. In the near future, the success of interventional therapies will most probably increase in patients with mitral PVLs with the introduction of hybrid imaging modalities (echocardiography, cardiac computed tomography, and fluoroscopy). In conclusion, this paper summarizes the etiopathogenesis, clinical characteristics, diagnosis, and treatment of mitral PVLs.
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