Evidence map›Paper›PMID 33252993›Full record

ArticlePhysiological genomics2021

Neuroanatomical characterization of Gαi

Parul Chaudhary, Richard D Wainford

Open access · greenAbstract read
In one paragraph

Article in Physiological genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Central GαiFrontiers in endocrinology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Parul ChaudharyDepartment of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts.ORCID 0000-0002-5181-6515
Richard D WainfordDepartment of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts.ORCID 0000-0003-2830-5618
Boston University · US

Funding

Multidisciplinary Training in Cardiovascular ResearchT32HL007224 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAMBURG, NAOMI MIRIAM, WAINFORD, RICHARD DAVID · 1985 to 2020
$12.3M
Aging and hypertension: Integrated renal and sympathetic control of blood pressureR01AG062515 · NIA · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2019 to 2023
$3.5M
Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressureR01HL141406 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.8M
Neural control of the kidney and long-term blood pressure regulationR01HL139867 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.6M
Brain G-alpha subunit protein mediated neural control of blood pressureR01HL107330 · NHLBI · LSU HEALTH SCIENCES CENTER · PI WAINFORD, RICHARD DAVID · 2011 to 2015
$1.9M
Aging and hypertension: Integrated renal and sympathetic control of blood pressureR56AG057687 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WAINFORD, RICHARD DAVID · 2018 to 2018
$731k
NHLBI NIH HHS R01 HL107330NHLBI NIH HHS R01 HL139867NHLBI NIH HHS R01 HL141406NHLBI NIH HHS T32 HL07224NIA NIH HHS R01 AG062515NIA NIH HHS R56 AG057687
6 · The paper itself

Abstract

Hypertension is a global health burden. The hypothalamic paraventricular nucleus (PVN) is an essential component of the neuronal network that regulates sodium homeostasis and blood pressure (BP). Previously, we have shown PVN-specific G protein-coupled receptor-coupled Gαi

Indexed as

AnimalsCorticotropin-Releasing HormoneFemaleGABAergic NeuronsGlutamic AcidGTP-Binding Protein alpha Subunit, Gi2MaleNeuronsOxytocinParaventricular Hypothalamic NucleusRatsRats, Sprague-DawleyTyrosine 3-MonooxygenaseCorticotropin-Releasing HormoneGlutamic AcidGnai2 protein, ratGTP-Binding Protein alpha Subunit, Gi2OxytocinTyrosine 3-MonooxygenaseGnai2 mRNAin situ hybridizationparvocellularPVN

Identifiers

PMID33252993
PMCPMC7847047
OpenAlexW3110168260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.