Evidence map›Paper›PMID 33252737›Full record

ReviewSub-cellular biochemistry2021

Structure, Function and Physiology of 5-Hydroxytryptamine Receptors Subtype 3.

Eric Gibbs, Sudha Chakrapani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sub-cellular biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Measuring serotonin binding to its receptorsbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Predicted conformations of 5-HT3 receptor ion channels are modified by subunit D.Computational and structural biotechnology journal · 2025
    Article
  6. Article
  7. Article
  8. Structural basis for partial agonism in 5-HTNature structural & molecular biology · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Tapping into 5-HTInternational journal of molecular sciences · 2021
    Review
  16. Direct Structural Insights into GABATrends in biochemical sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eric GibbsDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, 44106-4970, USA. edg42@case.edu.
Sudha ChakrapaniDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, 44106-4970, USA. sxc584@case.edu.
Case Western Reserve University · US

Funding

Structure and Function of Pentameric Ligand-Gated Ion ChannelsR35GM134896 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI Sudha Chakrapani · 2020 to 2026
$4.7M
MOLECULAR MECHANISMS OF DESENSITIZATION AND DRUG MODULATION IN LIGAND-GATED ION CHANNELSR01GM108921 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI CHAKRAPANI, SUDHA · 2014 to 2018
$1.9M
NIGMS NIH HHS R01 GM108921NIGMS NIH HHS R35 GM134896
6 · The paper itself

Abstract

5-hydroxytryptamine receptor subtype 3 (5-HT

Indexed as

HumansReceptors, Serotonin, 5-HT3SerotoninReceptors, Serotonin, 5-HT3Serotonin5-HT5-HT3RMembrane biophysicsNeurotransmissionPentameric ligand-gated ion channelSerotonin

Identifiers

PMID33252737
OpenAlexW3107058783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.