Evidence map›Paper›PMID 33252719›Full record

ArticlePhysical and engineering sciences in medicine2021

Automated measurement of hip-knee-ankle angle on the unilateral lower limb X-rays using deep learning.

Yun Pei, Wenzhuo Yang, Shangqing Wei, Rui Cai, Jialin Li, Shuxu Guo, Qiang Li, Jincheng Wang, Xueyan Li

Abstract read
In one paragraph

Article in Physical and engineering sciences in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yun Pei *State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, China.ORCID http://orcid.org/0000-0002-9624-7440
Wenzhuo Yang *Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Shangqing WeiSchool of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Rui CaiCollege of Clinical Medicine, Jilin University, Changchun, China.
Jialin LiCollege of Clinical Medicine, Jilin University, Changchun, China.
Shuxu GuoState Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, China.
Qiang LiDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China. gonggong0213@163.com.ORCID http://orcid.org/0000-0002-3989-0907
Jincheng WangDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China. bone@jlu.edu.cn.
Xueyan LiState Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, China. leexy@jlu.edu.cn.

Funding

Jilin Province Development and Reform Commission Project 2020C019-2National Key R&D Program of China 2016YFE0200700National Natural Science Foundation of China 61627820National Natural Science Foundation of China 61934003Natural Science Foundation of Jilin Province 20180101038JCScientific Development Program of Jilin Province 20170204004GXScientific Development Program of Jilin Province 3D516D733429Scientific Development Program of Jilin Province 3D5177743429
6 · The paper itself

Abstract

Significant inherent extra-articular varus angulation is associated with abnormal postoperative hip-knee-ankle (HKA) angle. At present, HKA is manually measured by orthopedic surgeons and it increases the doctors' workload. To automatically determine HKA, a deep learning-based automated method for measuring HKA on the unilateral lower limb X-rays was developed and validated. This study retrospectively selected 398 double lower limbs X-rays during 2018 and 2020 from Jilin University Second Hospital. The images (n = 398) were cropped into unilateral lower limb images (n = 796). The deep neural network was used to segment the head of hip, the knee, and the ankle in the same image, respectively. Then, the mean square error of distance between each internal point of each organ and the organ's boundary was calculated. The point with the minimum mean square error was set as the central point of the organ. HKA was determined using the coordinates of three organs' central points according to the law of cosines. In a quantitative analysis, HKA was measured manually by three orthopedic surgeons with a high consistency (176.90 °  ± 12.18°, 176.95 °  ± 12.23°, 176.87 °  ± 12.25°) as evidenced by the Kandall's W of 0.999 (p < 0.001). Of note, the average measured HKA by them (176.90 °  ± 12.22°) served as the ground truth. The automatically measured HKA by the proposed method (176.41 °  ± 12.08°) was close to the ground truth, showing no significant difference. In addition, intraclass correlation coefficient (ICC) between them is 0.999 (p < 0.001). The average of difference between prediction and ground truth is 0.49°. The proposed method indicates a high feasibility and reliability in clinical practice.

Indexed as

AnkleDeep LearningHipKneeLower ExtremityHumansReproducibility of ResultsRetrospective StudiesX-RaysAngle measurementDeep learningHKAX-ray

Identifiers

PMID33252719
PMCPMC7701936

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.