Evidence map›Paper›PMID 33252329›Full record

ArticleeLife2020

Presynaptic NMDARs cooperate with local spikes toward GABA release from the reciprocal olfactory bulb granule cell spine.

Vanessa Lage-Rupprecht, Li Zhou, Gaia Bianchini, S Sara Aghvami, Max Mueller, Balázs Rózsa, Marco Sassoè-Pognetto, Veronica Egger

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Vanessa Lage-RupprechtNeurophysiology, Institute of Zoology, Universität Regensburg, Regensburg, Germany.
Li ZhouNeurophysiology, Institute of Zoology, Universität Regensburg, Regensburg, Germany.
Gaia BianchiniNeurophysiology, Institute of Zoology, Universität Regensburg, Regensburg, Germany.
S Sara AghvamiNeurophysiology, Institute of Zoology, Universität Regensburg, Regensburg, Germany.
Max MuellerNeurophysiology, Institute of Zoology, Universität Regensburg, Regensburg, Germany.
Balázs RózsaTwo-Photon Imaging Center, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary.
Marco Sassoè-PognettoNeuroscience Department, University of Turin, Torino, Italy.
Veronica EggerNeurophysiology, Institute of Zoology, Universität Regensburg, Regensburg, Germany.ORCID 0000-0002-5869-8523
University of Regensburg · DEFraunhofer Institute for Algorithms and Scientific Computing · DEHUN-REN Institute of Experimental Medicine · HUUniversity of Tehran · IRUniversity of Turin · IT

Funding

Bundesministerium für Bildung und Forschung 01GQ1104/01GQ1502European Research Council 682426European Research Council 712821-NEURAMEuropean Research Council GINOP_2.1.1-15-2016-00979European Research Council VKSZ_14-1-2015-0155German-Israeli Foundation for Scientific Research and Development 1479-418.13Graduate School of Systemic Neurosciences GSN-LMU DFG SFB 870
6 · The paper itself

Abstract

In the rodent olfactory bulb the smooth dendrites of the principal glutamatergic mitral cells (MCs) form reciprocal dendrodendritic synapses with large spines on GABAergic granule cells (GC), where unitary release of glutamate can trigger postsynaptic local activation of voltage-gated Na

Indexed as

Action PotentialsAnimalsAnimals, Genetically ModifiedCalcium ChannelsDendritic CellsElectric StimulationFemalegamma-Aminobutyric AcidGene Expression RegulationIon Channel GatingMaleNeuronsOlfactory BulbPatch-Clamp TechniquesRatsRats, WistarCalcium Channelsgamma-Aminobutyric AcidReceptors, N-Methyl-D-AspartateSodium Channelsgranule cellmitral cellneuroscienceolfactory bulbpresynaptic NMDA receptorratreciprocal synapse

Identifiers

PMID33252329
PMCPMC7704106
OpenAlexW3108104786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.