Evidence map›Paper›PMID 33252215›Full record

ReviewACS nano2020

Microfluidic Isolation and Enrichment of Nanoparticles.

Yuliang Xie, Joseph Rufo, Ruoyu Zhong, Joseph Rich, Peng Li, Kam W Leong, Tony Jun Huang

Abstract readReview
In one paragraph

Review in ACS nano, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Isolation Techniques of Micro/Nano-Scaled Species for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Article
  7. Exosome: an overview on enhanced biogenesis by small molecules.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Microfluidic Nanoparticle Separation for Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuliang XieRoy J. Carver Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa 52242, United States.
Joseph RufoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.
Ruoyu ZhongDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.
Joseph RichDepartment of Biomedical Engineering, Duke University, Durham, North Carolina 27708, United States.
Peng LiC. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, United States.ORCID 0000-0002-8332-7142
Kam W LeongDepartment of Biomedical Engineering, Columbia University, New York, New York 10032, United States.ORCID 0000-0002-8133-4955
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0003-1205-3313

Funding

Extracellular vesicles and their ncRNA cargo as markers of trophoblast injuryR01HD086325 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SADOVSKY, YOEL · 2015 to 2019
$3.6M
Integrated Acoustofluidic Plasmonic Molecular Diagnostic System for Detecting MicroRNA BiomarkersR01GM135486 · NIGMS · DUKE UNIVERSITY · PI VO-DINH, TUAN · 2020 to 2023
$1.8M
Enabling Efficient, Fast, Biocompatible Exosome Separation via AcoustofluidicsR01GM132603 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2019 to 2022
$1.7M
Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platformR33CA223908 · NCI · NORTHEASTERN UNIVERSITY · PI EVENS, ANDREW M, HUANG, TONY JUN · 2018 to 2020
$1.2M
An integrated acoustofluidic droplet-sorting platform for classification of lymphocyte activity and functional phenotyping at single cell levelR01GM127714 · NIGMS · NORTHEASTERN UNIVERSITY · PI KONRY, TANIA TALI · 2018 to 2021
$1.2M
Acoustofluidic Separation (AFS), Purification and Raman Spectral Fingerprinting of Single EVs: From Cell of Origin to Target Cell and BiofluidsUG3TR002978 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AN, JI YEONG, GALL, KENNETH A · 2019 to 2020
$823k
NCATS NIH HHS UG3 TR002978NCI NIH HHS R33 CA223908NICHD NIH HHS R01 HD086325NIGMS NIH HHS R01 GM127714NIGMS NIH HHS R01 GM132603NIGMS NIH HHS R01 GM135486
6 · The paper itself

Abstract

Over the past decades, nanoparticles have increased in implementation to a variety of applications ranging from high-efficiency electronics to targeted drug delivery. Recently, microfluidic techniques have become an important tool to isolate and enrich populations of nanoparticles with uniform properties (

Indexed as

acoustofluidicsdeterministic lateral displacementdielectrophoresisenrichmentinertial microfluidicsisolationmicrofiltrationmicrofluidicsnanoparticlesoptofluidics

Identifiers

PMID33252215
PMCPMC8164652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.