ArticleMagnetic resonance in medicine2021
Free-breathing diffusion tensor MRI of the whole left ventricle using second-order motion compensation and multitasking respiratory motion correction.
Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 39 citations in OpenAlex.
- Optimized Reduced Field of View and Fat Suppression Methods for Interleaved Multislice In Vivo Cardiac Diffusion Tensor Imaging.Magnetic resonance in medicine · 2026Article
- Evaluation of Third-Order Motion-Compensated Cardiac Diffusion Tensor Imaging Across Cardiac Phases Using an Ultra-High-Performance Clinical Scanner.Magnetic resonance in medicine · 2026Article
- Voxel-scale diffusion tensor phenomapping of the healthy and pressure-overloaded human heart.Nature biomedical engineering · 2026Article
- Free-Breathing Multi-Slice Co-Registered Cardiac T1, T2, and ADC Mapping With Spin-Echo Echo Planar Imaging.Magnetic resonance in medicine · 2026Article
- Diffusion Tensor MRI of the Heart: The Toolbox Continues to Grow.Circulation. Cardiovascular imaging · 2026Article
- Comparison of cardiac diffusion MRI using multiple prospective respiratory motion correction techniques.Magnetic resonance in medicine · 2026Article
- GLOW: Gastric LOW-Rank Tensor-Based Motion Correction for Abdominal 4D MRI.NMR in biomedicine · 2025Article
- Platelet derived growth factor-AB modulates post-infarct myocardium leading to extended improvement in cardiac function.NPJ Regenerative medicine · 2025Article
- Engineering clinical translation of OGSE diffusion MRI.Magnetic resonance in medicine · 2025Review
- Toward optimal inline respiratory motion correction for in vivo cardiac diffusion tensor MRI using symmetric and inverse-consistent deformable image registration.Magnetic resonance in medicine · 2025Article
- In vivo cardiac diffusion tensor imaging on an MR system featuring ultrahigh performance gradients with 200 mT/m maximum gradient strength.Magnetic resonance in medicine · 2025Article
- In vivo diffusion MRI of the human heart using a 300 mT/m gradient system.Magnetic resonance in medicine · 2024Article
- Next-Generation Cardiac Magnetic Resonance Imaging Techniques for Characterization of Myocardial Disease.Current treatment options in cardiovascular medicine · 2024Article
- Cardiac DTI using short-axis PROPELLER: A feasibility study.Magnetic resonance in medicine · 2024Article
- Facilitating diffusion tensor imaging of the brain during continuous gross head motion with first and second order motion compensating diffusion gradients.Magnetic resonance in medicine · 2024Article
- The future of cardiovascular magnetic resonance: All-in-one vs. real-time (Part 1).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Review
- Contrast-Enhanced Cardiac Magnetic Resonance Imaging With a Manganese-Based Alternative to Gadolinium for Tissue Characterization of Acute Myocardial Infarction.Journal of the American Heart Association · 2023Article
- Accelerating Cardiac Diffusion Tensor Imaging With a U-Net Based Model: Toward Single Breath-Hold.Journal of magnetic resonance imaging : JMRI · 2022Article
- Exercise-induced CITED4 expression is necessary for regional remodeling of cardiac microstructural tissue helicity.Communications biology · 2022Article
- Comparison of interpolation methods of predominant cardiomyocyte orientation from in vivo and ex vivo cardiac diffusion tensor imaging data.NMR in biomedicine · 2022Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
purposeWe aimed to develop a novel free-breathing cardiac diffusion tensor MRI (DT-MRI) approach, M2-MT-MOCO, capable of whole left ventricular coverage that leverages second-order motion compensation (M2) diffusion encoding and multitasking (MT) framework to efficiently correct for respiratory motion (MOCO).
methodsImaging was performed in 16 healthy volunteers and 3 heart failure patients with symptomatic dyspnea. The healthy volunteers were scanned to compare the accuracy of interleaved multislice coverage of the entire left ventricle with a single-slice acquisition and the accuracy of the free-breathing conventional MOCO and MT-MOCO approaches with reference breath-hold DT-MRI. Mean diffusivity (MD), fractional anisotropy (FA), helix angle transmurality (HAT), and intrascan repeatability were quantified and compared.
resultsIn all subjects, free-breathing M2-MT-MOCO DT-MRI yielded DWI of the entire left ventricle without bulk motion-induced signal loss. No significant differences were seen in the global values of MD, FA, and HAT in the multislice and single-slice acquisitions. Furthermore, global quantification of MD, FA, and HAT were also not significantly different between the MT-MOCO and breath-hold, whereas conventional MOCO yielded significant differences in MD, FA, and HAT with MT-MOCO and FA with breath-hold. In heart failure patients, M2-MT-MOCO DT-MRI was feasible yielding higher MD, lower FA, and lower HAT compared with healthy volunteers. Substantial agreement was found between repeated scans across all subjects for MT-MOCO.
conclusionM2-MT-MOCO enables free-breathing DT-MRI of the entire left ventricle in 10 min, while preserving quantification of myocardial microstructure compared to breath-held and single-slice acquisitions and is feasible in heart failure patients.
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