ArticleJournal of Alzheimer's disease : JAD2021
Mortality in Dementia from 1996 to 2015: A National Registry-Based Cohort Study.
Article in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of the COVID-19 pandemic on mortality in people with dementia without COVID-19: a systematic review and meta-analysis.BMC geriatrics · 2022Pooled it
- Mortality of people with diagnosed dementia in Germany between 2016 and 2021.Alzheimer's research & therapy · 2026Article
- Development of a mortality prediction nomogram for dementia patients using the MIMIC-IV database.Scientific reports · 2026Article
- Experiences of bereaved family caregivers of patients with Alzheimer's disease regarding do-not-resuscitate orders: A qualitative study.Palliative & supportive care · 2026Article
- TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Dementia's mortality in America: a local, regional, and temporal evaluation.Dementia & neuropsychologia · 2026Article
- Thirty-seven-year trends in the prevalence, incidence, and prognosis of dementia in a Japanese community: the Hisayama study.Alzheimer's research & therapy · 2025Article
- Secular trends in incidence, survival, and health status at diagnosis of dementia in Sweden, 2007-2022.Alzheimer's research & therapy · 2025Article
- Cholinesterase inhibitors associated with lower rate of mortality in dementia patients with heart failure: a nationwide propensity weighting study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Article
- Neighborhood disadvantage and the risk of dementia and mortality among refugees to Denmark: A quasi-experimental study.SSM - population health · 2023Article
- Effects of Dementia on Outcomes after Cervical Spine Injuries in Elderly Patients: Evaluation of 1512 Cases in a Nationwide Multicenter Study in Japan.Journal of clinical medicine · 2023Article
- Identification of diagnostic molecules and potential traditional Chinese medicine components for Alzheimer's disease by single cell RNA sequencing combined with a systematic framework for network pharmacology.Frontiers in medicine · 2023Article
- Causal association between colorectal cancer and Alzheimer's disease: a bidirectional two-sample mendelian randomization study.Frontiers in genetics · 2023Article
- A Bibliometric and Visual Analysis of Exercise Intervention Publications for Alzheimer's Disease (1998-2021).Journal of clinical medicine · 2022Article
- Association of Acute Kidney Injury with the Risk of Dementia: A Meta-Analysis.Journal of clinical medicine · 2021Article
- Article
- Causes of Death in People with Dementia from 2002 to 2015: A Nationwide Study.Journal of Alzheimer's disease : JAD · 2021Article
- The impact of population aging on the mortality rate of dementia among residents in Suzhou, China, 2004-2023.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt remains unclear whether the increased focus on improving healthcare and providing appropriate care for people with dementia has affected mortality.
objectiveTo assess survival and to conduct a time trend analysis of annual mortality rate ratios (MRR) of dementia based on healthcare data from an entire national population.
methodsWe assessed survival and annual MRR in all residents of Denmark ≥65 years from 1996-2015 using longitudinal registry data on dementia status and demographics. For comparison, mortality and survival were calculated for acute ischemic heart disease (IHD) and cancer.
resultsThe population comprised 1,999,366 people (17,541,315 person years). There were 165,716 people (529,629 person years) registered with dementia, 131,321 of whom died. From 1996-2015, the age-adjusted MRR for dementia declined (women: 2.76 to 2.05; men: 3.10 to 1.99) at a similar rate to elderly people without dementia. The sex-, age-, and calendar-year-adjusted MRR was 2.91 (95%CI: 2.90-2.93) for people with dementia. MRR declined significantly more for acute IHD and cancer. In people with dementia, the five-year survival for most age-groups was at a similar level or lower as that for acute IHD and cancer.
conclusionAlthough mortality rates declined over the 20-year period, MRR stayed higher for people with dementia, while the MRR gap, compared with elderly people without dementia, remained unchanged. For the comparison, during the same period, the MRR gap narrowed between people with and without acute IHD and cancer. Consequently, initiatives for improving health and decreasing mortality in dementia are still highly relevant.
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