Evidence map›Paper›PMID 33251934›Full record

ArticleVirulence2020

Role of LFA-1 integrin in the control of a lymphocytic choriomeningitis virus (LCMV) infection.

Mario Perro, Matteo Iannacone, Ulrich H von Andrian, Antonio Peixoto

Abstract read
In one paragraph

Article in Virulence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mario PerroHarvard Medical School , Department of Microbiology and Immunobiology, Boston, Massachusetts, USA.ORCID 0000-0003-1375-8155
Matteo IannaconeHarvard Medical School , Department of Microbiology and Immunobiology, Boston, Massachusetts, USA.ORCID 0000-0002-9370-2671
Ulrich H von AndrianHarvard Medical School , Department of Microbiology and Immunobiology, Boston, Massachusetts, USA.
Antonio PeixotoHarvard Medical School , Department of Microbiology and Immunobiology, Boston, Massachusetts, USA.ORCID 0000-0001-9493-1954

Funding

T Cell Activation in Lymph NodesR01AI069259 · NIAID · IMMUNE DISEASE INSTITUTE, INC. · PI VON ANDRIAN, ULRICH H · 2006 to 2015
$4.5M
NIAID NIH HHS R01 AI069259
6 · The paper itself

Abstract

Leukocyte function-associated antigen 1 (LFA-1) is the most widely expressed member of the β2 integrin family of cell-cell adhesion molecules. Although LFA-1 is thought to regulate multiple aspects of T cell immunity, its role in the response of CD8

Indexed as

AnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DifferentiationDisease Models, AnimalGene Expression ProfilingLymphocyte ActivationLymphocyte Function-Associated Antigen-1Lymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMiceMice, Inbred C57BLMice, TransgenicLymphocyte Function-Associated Antigen-1IntegrinLCMVT cell activationT cell differentiation

Identifiers

PMID33251934
PMCPMC7714442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.