Trial reportJournal of the American Heart Association2021
New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting and Long-Term Outcome: A Population-Based Nationwide Study From the SWEDEHEART Registry.
Trial report in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06800781 (Prolonged Posterior Pericardial Chest Tube Treatment to Reduce Rates of Postoperative Atrial Fibrillation Following Cardiac Surgery), which is not on this map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prolonged Posterior Pericardial Chest Tube Treatment to Reduce Rates of Postoperative Atrial Fibrillation Following Cardiac Surgery
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- Effect of Postoperative Atrial Fibrillation After Cardiac Surgery: A Meta-Analysis.Clinical cardiology · 2024Pooled it
- Effect of posterior pericardiotomy in cardiac surgery: A systematic review and meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2022Pooled it
- Incidence, Risk Factors, and Outcomes in Stressor-Associated Atrial Fibrillation: Insights From the VITAL-AF Trial.Circulation · 2026Trial
- Targeted ablation of epicardial ganglionated plexi during cardiac surgery with pulsed field electroporation (NEURAL AF).Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Trial
- Early anti-coagulation therapy in new-onset atrial fibrillation after coronary artery bypass grafting: a randomized trial pilot study.BMC cardiovascular disorders · 2024Trial
- New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting and Long-Term Outcome: A Population-Based Nationwide Study From the SWEDEHEART Registry.Journal of the American Heart Association · 2021Trial
- Thromboembolic and Mortality Risk in Patients with Postoperative Atrial Fibrillation After Coronary Artery Bypass Graft-The TRIP-AF Study.Journal of clinical medicine · 2026Article
- Bleeding risk assessment in patients with new-onset atrial fibrillation after coronary surgery: a proof-of-concept study.European heart journal. Cardiovascular pharmacotherapy · 2026Observational
- The anticoagulation dilemma in post-operative atrial fibrillation after cardiac surgery.European heart journal. Cardiovascular pharmacotherapy · 2026Article
- Postoperative atrial fibrillation as an independent predictor of 90-day complications in geriatric patients undergoing coronary artery bypass grafting.Journal of geriatric cardiology : JGC · 2026Article
- Health-Related Quality of Life and Associated Factors Before and After Coronary Artery Bypass Grafting: A Multicentre Prospective Study in Cyprus.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Practical Recommendations for Anticoagulation in Patients With Atrial Fibrillation.European journal of clinical investigation · 2026Review
- Review
- Nonlinear association and threshold effect between preoperative estimated pulse wave velocity and postoperative atrial fibrillation after coronary artery bypass grafting.Journal of thoracic disease · 2026Article
- Preoperative Inflammatory Burden Index Predicts Atrial Fibrillation After Coronary Artery Bypass Grafting: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Predicting postoperative atrial fibrillation: a pragmatic risk score based on preoperative factors.Journal of thoracic disease · 2026Article
- C-Reactive Protein-to-Albumin Ratio (CAR) and Left Atrial Diameter Predicts New-Onset Atrial Fibrillation in Chronic Coronary Syndrome: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Trends and Outcomes of Anticoagulation for Post-Operative Atrial Fibrillation After Coronary Artery Bypass Graft.Pacing and clinical electrophysiology : PACE · 2025Article
- Observational
- Impact of postoperative atrial fibrillation (POAF) on outcomes after coronary artery bypass grafting: A meta-analysis of unique 247,270 patients from 50 studies.American heart journal plus : cardiology research and practice · 2025Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background The long-term impact of new-onset postoperative atrial fibrillation (POAF) after coronary artery bypass grafting and the benefit of early-initiated oral anticoagulation (OAC) in patients with POAF are uncertain. Methods and Results All patients who underwent coronary artery bypass grafting without preoperative atrial fibrillation in Sweden from 2007 to 2015 were included in a population-based study using data from 4 national registries: SWEDEHEART (Swedish Web System for Enhancement and Development of Evidence-based Care in Heart Disease Evaluated According to Recommended Therapies), National Patient Registry, Dispensed Drug Registry, and Cause of Death Registry. POAF was defined as any new-onset atrial fibrillation during the first 30 postoperative days. Cox regression models (adjusted for age, sex, comorbidity, and medication) were used to assess long-term outcome in patients with and without POAF, and potential associations between early-initiated OAC and outcome. In a cohort of 24 523 patients with coronary artery bypass grafting, POAF occurred in 7368 patients (30.0%), and 1770 (24.0%) of them were prescribed OAC within 30 days after surgery. During follow-up (median 4.5 years, range 0‒9 years), POAF was associated with increased risk of ischemic stroke (adjusted hazard ratio [aHR] 1.18 [95% CI, 1.05‒1.32]), any thromboembolism (ischemic stroke, transient ischemic attack, or peripheral arterial embolism) (aHR 1.16, 1.05‒1.28), heart failure hospitalization (aHR 1.35, 1.21‒1.51), and recurrent atrial fibrillation (aHR 4.16, 3.76‒4.60), but not with all-cause mortality (aHR 1.08, 0.98‒1.18). Early initiation of OAC was not associated with reduced risk of ischemic stroke or any thromboembolism but with increased risk for major bleeding (aHR 1.40, 1.08‒1.82). Conclusions POAF after coronary artery bypass grafting is associated with negative prognostic impact. The role of early OAC therapy remains unclear. Studies aiming at reducing the occurrence of POAF and its consequences are warranted.
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