Evidence map›Paper›PMID 33251651›Full record

ReviewInternational journal of clinical practice2021

Which drugs are best for overactive bladder? From patients' expectations to physicians' decisions.

Ian Milsom, Adrian Wagg, Matthias Oelke, Christopher Chapple

Open access · hybridAbstract readReview
In one paragraph

Review in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Ian MilsomDepartment of Obstetrics and Gynecology, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-0400-5509
Adrian WaggDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Matthias OelkeDepartment of Urology, Pediatric Urology and Urologic Oncology, St. Antonius Hospital, Gronau, Germany.
Christopher ChappleDepartment of Urology, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, United Kingdom.
Royal Hallamshire Hospital · GBSahlgrenska University Hospital · SESt.-Antonius-Hospital Gronau · DEUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIn order to help physicians determine which drugs are the best for treating overactive bladder (OAB) symptoms, this review considered three questions: what are the patient's expectations? What information is generated by the Multicriteria Decision Analysis (MCDA) model? What can physicians expect from medical treatments?

methodsA comprehensive literature search was undertaken on these three topics in order to assist physicians regarding the optimum treatment modality for OAB.

resultsPatients' difficulties in reporting symptoms and their expectations of treatment outcomes interfere with the success of treatment. To assist physicians in meeting patients' expectations and to choose the most appropriate treatment, a new approach, recognised by the European Medicines Agency, the MCDA model was used to compare the benefits and safety of OAB treatments.

conclusionThe MCDA model is useful for comparing the benefit-safety profiles of OAB drugs in order to equip clinicians with information on the drug that might best meet their patient's needs. Flexibly dosed fesoterodine appeared to be most efficacious in resolving urgency and urgency incontinence compared with other drugs, and resolution of urinary urgency appears to be associated with a reduced number of reported adverse events.

Indexed as

Pharmaceutical PreparationsPhysiciansUrinary Bladder, OveractiveBenzhydryl CompoundsHumansMotivationMuscarinic AntagonistsTreatment OutcomeBenzhydryl CompoundsMuscarinic AntagonistsPharmaceutical Preparationsfesoterodinemulticriteria decision analysisoveractive bladderpatient expectationstreatment comparisonurgency

Identifiers

PMID33251651
PMCPMC8047881
OpenAlexW3109402094

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.