Evidence map›Paper›PMID 33251429›Full record

ArticleACS omega2020

Computational Approaches to Identify Molecules Binding to

Ana C Puhl, Thomas R Lane, Patricia A Vignaux, Kimberley M Zorn, Glenn C Capodagli, Matthew B Neiditch, Joel S Freundlich, Sean Ekins

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Machine Learning Models forMolecular pharmaceutics · 2022
    Article
  6. Frontiers in cellular and infection microbiology · 2022
    Review
  7. Review
  8. Article
  9. Structure-basedComputational and structural biotechnology journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ana C PuhlCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Thomas R LaneCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Patricia A VignauxCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Kimberley M ZornCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Glenn C CapodagliDepartment of Microbiology, Biochemistry, and Molecular Genetics, Rutgers University - New Jersey Medical School, Newark, New Jersey 07103, United States.
Matthew B NeiditchDepartment of Microbiology, Biochemistry, and Molecular Genetics, Rutgers University - New Jersey Medical School, Newark, New Jersey 07103, United States.
Joel S FreundlichDepartment of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, Newark, New Jersey 07103, United States.
Sean EkinsCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Collaborations Pharmaceuticals (United States) · USRutgers, The State University of New Jersey · US

Funding

Structure-guided optimization of an in vivo active small molecule antitubercular targeting KasAR41AI134561 · NIAID · COLLABORATIONS PHARMACEUTICALS, INC. · PI EKINS, SEAN, FREUNDLICH, JOEL STEPHEN · 2018 to 2018
$225k
Centralized assay datasets for modelling support of small drug discovery organizationsR43GM122196 · NIGMS · COLLABORATIONS PHARMACEUTICALS, INC. · PI EKINS, SEAN · 2017 to 2017
$150k
NIAID NIH HHS R41 AI134561NIGMS NIH HHS R43 GM122196
6 · The paper itself

Abstract

Tuberculosis is caused by

Identifiers

PMID33251429
PMCPMC7689923
OpenAlexW3101739617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.