Evidence map›Paper›PMID 33251341›Full record

ArticleBiochemistry and biophysics reports2020

Exploring the binding interactions of structurally diverse dichalcogenoimidodiphosphinate ligands with α-amylase: Spectroscopic approach coupled with molecular docking.

Oghenetega J Avwioroko, Temidayo T Oyetunde, Francis O Atanu, Chiagoziem A Otuechere, Akpovwehwee A Anigboro, Oluropo F Dairo, Akpoyovware S Ejoh, Sunday O Ajibade, Martins O Omorogie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Green Synthesis of Novel Silver Nanoparticles UsingInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Oghenetega J AvwiorokoDepartment of Biochemistry, Faculty of Basic Medical Sciences, Redeemer's University, Ede, Osun State, Nigeria.
Temidayo T OyetundeDepartment of Chemical Sciences, Faculty of Natural Sciences, Redeemer's University, Ede, Osun State, Nigeria.
Francis O AtanuDepartment of Biochemistry, Faculty of Natural Sciences, Kogi State University, Anyigba, Nigeria.
Chiagoziem A OtuechereDepartment of Biochemistry, Faculty of Basic Medical Sciences, Redeemer's University, Ede, Osun State, Nigeria.
Akpovwehwee A AnigboroDepartment of Biochemistry, Faculty of Science, Delta State University, Abraka, Nigeria.
Oluropo F DairoDepartment of Physical Sciences, Faculty of Natural Sciences, Redeemer's University, Ede, Osun State, Nigeria.
Akpoyovware S EjohDepartment of Biological Sciences, Covenant University, Ota, Ogun State, Nigeria.
Sunday O AjibadeDepartment of Chemical Sciences, Faculty of Natural Sciences, Redeemer's University, Ede, Osun State, Nigeria.
Martins O OmorogieDepartment of Chemical Sciences, Faculty of Natural Sciences, Redeemer's University, Ede, Osun State, Nigeria.
Redeemer's University · NGCovenant University · NGDelta State University · NGKogi State University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postprandial hyperglycemia has orchestrated untimely death among diabetic patients over the decades and regulation of α-amylase activity is now becoming a promising management option for type 2 diabetes. The present study investigated the binding interactions of three structurally diverse dichalcogenoimidodiphosphinate ligands with α-amylase to ascertain the affinity of the ligands for α-amylase using spectroscopic and molecular docking methods. The ligands were characterized using

Indexed as

Anti-diabetic agentsHyperglycemiaLigand-protein bindingSpectroscopyα-Amylase inhibition

Identifiers

PMID33251341
PMCPMC7677685
OpenAlexW3106208822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.