ArticleFrontiers in veterinary science2020
EEG Patterns Orienting to Lafora Disease Diagnosis-A Case Report in Two Beagles.
Article in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Current knowledge of intermittent photic stimulation for electroencephalography in dogs.Journal of veterinary internal medicine · 2026Review
- Phenotypic characterization of presumptive propriospinal myoclonus in young dogs (2013-2025).Journal of veterinary internal medicine · 2026Article
- Axonal polyneuropathy in Lafora disease with a newly identified EPM2A mutation: a case report and review of literature.Journal of neurology · 2025Article
- Article
- Electroencephalography: electrode arrays in dogs.Frontiers in veterinary science · 2024Review
- Article
- A retrospective case series of clinical signs in 28 Beagles with Lafora disease.Journal of veterinary internal medicine · 2021Article
- A Novel Mutation in Lafora Disease and Update on Pathophysiology and Future Treatments.Child neurology openArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lafora Disease (LD) is a rare, fatal, late-onset, progressive form of myoclonic epilepsy, occurring in humans and dogs. Clinical manifestations of LD usually include seizures, spontaneous and reflex myoclonus with contractions of the neck and limb muscles. We studied the electroencephalogram (EEG) patterns of two beagles in whom LD was subsequently confirmed by genetic testing. In both cases, the EEG recordings, accompanied by electromyography (EMG), have shown similar uncommon patterns. The hypovoltaged background rhythm was interrupted by waxing "crescendo" polyspikes-slow wave complexes appearing 80-250 ms after the start of intermittent photic stimulation, followed by myoclonic jerks after 80-150 ms. This study highlights the value of EEG in establishing a presumptive diagnosis of LD in dogs.
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