ReviewFrontiers in public health2020
The Opioid/Overdose Crisis as a Dialectics of Pain, Despair, and One-Sided Struggle.
Review in Frontiers in public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- A Systematic Review of Simulation Models to Track and Address the Opioid Crisis.Epidemiologic reviews · 2022Pooled it
- Effectiveness of Interventions for Prevention of Common Infections Among Opioid Users: A Systematic Review of Systematic Reviews.Frontiers in public health · 2022Pooled it
- Socioenvironmental disasters and the dialectics of overdose mortality.The International journal on drug policy · 2026Article
- Prehabilitation Reimagined as Policy: A Multidimensional Framework to Reduce Pain, Opioid Use, and Surgical Risk.International journal of spine surgery · 2025Article
- Maximizing the Public Health Benefits of Opioid Settlements: Policy Recommendations for Equity, Sustainability, and Impact.The Milbank quarterly · 2025Article
- Dialectical Processes of Health Framework as an Alternative to Social Determinants of Health Framework.American journal of public health · 2025Article
- The effect of lifting eviction moratoria on fatal drug overdoses in the context of the COVID-19 pandemic in the United States.American journal of epidemiology · 2025Article
- Spatiotemporal forecasting of opioid-related fatal overdoses: towards best practices for modeling and evaluation.American journal of epidemiology · 2025Article
- Geographical narcissism and Ontario's opioid crisis.Canadian journal of public health = Revue canadienne de sante publique · 2025Article
- Sociodemographic and clinical characteristics associated with overdose among patients with a substance-related diagnosis in the emergency department of Southern California.Harm reduction journal · 2025Article
- Early detection and prediction of non-fatal drug-related incidents and fatal overdose outbreaks using the Farrington algorithm.Addiction (Abingdon, England) · 2025Article
- Recovery-based suicide prevention.Frontiers in psychiatry · 2025Article
- Top Three Healthcare Trends in Orthopaedics Affecting Musculoskeletal Care in the Elderly.Current aging science · 2025Review
- Historical and theoretical roots of the big events framework.The International journal on drug policy · 2024Article
- What would it really take to solve the overdose epidemic in the United States?The International journal on drug policy · 2024Article
- A Pharmacogenomics-Based In Silico Investigation of Opioid Prescribing in Post-operative Spine Pain Management and Personalized Therapy.Cellular and molecular neurobiology · 2024Article
- The Imperative of Regulation: The Co-creation of a Medical and Non-medical US Opioid Crisis.Psychoactives · 2023Article
- Association of globalization with the burden of opioid use disorders 2019. A country-level analysis using targeted maximum likelihood estimation.Globalization and health · 2023Article
- A small molecule ligand for the novel pain target, GPR171, produces minimal reward in mice.Pharmacology, biochemistry, and behavior · 2023Article
- Geography, rurality, and community distress: deaths due to suicide, alcohol-use, and drug-use among Colorado Veterans.Injury epidemiology · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
The opioid/overdose crisis in the United States and Canada has claimed hundreds of thousands of lives and has become a major field for research and interventions. It has embroiled pharmaceutical companies in lawsuits and possible bankruptcy filings. Effective interventions and policies toward this and future drug-related outbreaks may be improved by understanding the sociostructural roots of this outbreak. Much of the literature on roots of the opioid/overdose outbreak focuses on (1) the actions of pharmaceutical companies in inappropriately promoting the use of prescription opioids; (2) "deaths of despair" based on the deindustrialization of much of rural and urban Canada and the United States, and on the related marginalization and demoralization of those facing lifetimes of joblessness or precarious employment in poorly paid, often dangerous work; and (3) increase in occupationally-induced pain and injuries in the population. All three of these roots of the crisis-pharmaceutical misconduct and unethical marketing practices, despair based on deindustrialization and increased occupational pain-can be traced back, in part, to what has been called the "one-sided class war" that became prominent in the 1970s, became institutionalized as neo-liberalism in and since the 1980s, and may now be beginning to be challenged. We describe this one-sided class war, and how processes it sparked enabled pharmaceutical corporations in their misconduct, nurtured individualistic ideologies that fed into despair and drug use, weakened institutions that created social support in communities, and reduced barriers against injuries and other occupational pain at workplaces by reducing unionization, weakening surviving unions, and weakening the enforcement of rules about workplace safety and health. We then briefly discuss the implications of this analysis for programs and policies to mitigate or reverse the opioid/overdose outbreak.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.