Evidence map›Paper›PMID 33251070›Full record

ReviewCureus2020

Chemotherapy and Immunosuppressant Therapy-Induced Posterior Reversible Encephalopathy Syndrome.

Gurleen Kaur, Ibtisam Ashraf, Mercedes Maria Peck, Ruchira Maram, Alaa Mohamed, Diego Ochoa Crespo, Bilal Haider Malik

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Gurleen KaurNeurology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ibtisam AshrafInternal Medicine, Shalamar Institute of Health Sciences, Lahore, PAK.
Mercedes Maria PeckInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ruchira MaramInternal Medicine, Arogyasri Healthcare Trust, Hyderabad, IND.
Alaa MohamedInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Diego Ochoa CrespoInternal Medicine, Clinica San Martin, Azogues, ECU.
Bilal Haider MalikInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Memorial Hermann–Texas Medical Center · USShalamar Hospital · PKCalifornia Institute of Behavioral Neurosciences and Psychology (United States) · USNottinghamshire Healthcare NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posterior reversible encephalopathy syndrome (PRES) is an entity which is characterized by acute to subacute onset of neurological symptoms like altered mental status, seizures, headaches and other focal neurological deficits. It is diagnosed with the help of MRI findings which typically involve the subcortical white matter of parieto-occipital lobes. In this review, we will discuss the various etiologies and risk factors including some of the most common chemotherapeutic agents and immunosuppressant agents associated with this disorder. We will discuss the mechanism of actions and side effect profiles of a few drugs and their role in causation of PRES. This review article discusses if there is any difference in presentation and imaging findings of PRES caused by cytotoxic agents versus caused by other etiologies. It also highlights the difficulty in management of PRES caused by cytotoxic agents as the discontinuation of these drugs could be life-threatening due to graft rejections or graft versus host disease.

Indexed as

chemotherapyimmunosuppressantposterior reversible encephalopathy syndrome (pres)radiological findings in prestacrolimus

Identifiers

PMID33251070
PMCPMC7688184
OpenAlexW3096779416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.