Evidence map›Paper›PMID 33251025›Full record

ArticleJournal of virus eradication2020

Re-examining the HIV 'functional cure' oxymoron: Time for precise terminology?

Karine Dubé, Loreen Willenberg, Lynda Dee, Laurie Sylla, Jeff Taylor, Christopher Roebuck, David Palm, Danielle Campbell, Luke Newton, Hursch Patel and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virus eradication, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Karine DubéUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
Loreen WillenbergZephyr LTNP Foundation, Inc., Sacramento, CA, USA.
Lynda DeeAIDS Action Baltimore, Baltimore, MD, USA.
Laurie SyllaMartin Delaney Collaboratory CAB, Baltimore, MD; Seattle, WA; Palm Springs, CA; Ithaca, NY, Los Angeles, CA, USA.
Jeff TayloramfAR Institute for HIV Cure Research Community Advisory Board (CAB), Palm Springs, CA, USA.
Christopher RoebuckMartin Delaney Collaboratory CAB, Baltimore, MD; Seattle, WA; Palm Springs, CA; Ithaca, NY, Los Angeles, CA, USA.
David PalmMartin Delaney Collaboratory CAB, Baltimore, MD; Seattle, WA; Palm Springs, CA; Ithaca, NY, Los Angeles, CA, USA.
Danielle CampbellDelaney AIDS Research Enterprise (DARE) CAB, Baltimore,MD and Los, Angeles, CA, USA.
Luke NewtonUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
Hursch PatelUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
Kelly E PerryUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
John KanazawaUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
Jo GerrardUniversity of California Riverside School of Medicine, Riverside, CA, USA.
Brandon BrownCenter for Healthy Communities, Department of Social Medicine and Population Health, University of California Riverside School of Medicine, Riverside, CA, USA.
Parya SaberiDivision of Prevention Science, Center for AIDS Prevention Studies, University of California, San Francisco, CA, USA.
John A SaucedaDivision of Prevention Science, Center for AIDS Prevention Studies, University of California, San Francisco, CA, USA.
Michael J PelusoDivision of HIV, Infectious Diseases and Global Medicine, University of California, San Francisco, CA, USA.

Funding

Cell and Gene Therapy for HIV CureUM1AI126623 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI JEROME, KEITH R, KIEM, HANS-PETER · 2016 to 2020
$24.2M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
Perceptions of Risks and Benefits of Participating in HIV Cure-related Research among Diverse Youth and Young Adults Living with HIV in the United StatesR21MH122280 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DUBE, KARINE, SABERI, PARYA · 2020 to 2021
$458k
NIAID NIH HHS T32 AI060530NIAID NIH HHS UM1 AI126623NIDA NIH HHS T32 DA023356NIMH NIH HHS R21 MH122280
6 · The paper itself

Abstract

For over a decade, the binary concepts of 'sterilizing'

Indexed as

Community engagementControlFunctional cureHIVHIV cure researchImmunityJournal of virus eradicationLanguageSuppressionTerminology

Identifiers

PMID33251025
PMCPMC7646673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.