ArticleAnnals of medicine and surgery (2012)2020
Diagnostic challenge in diagnosing bilateral breast metastases from mediastinal neuroendocrine tumor: A case report.
Article in Annals of medicine and surgery (2012), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed, 4 citations in OpenAlex.
- Bilateral breast metastases as the first manifestation of an occult pancreatic neuroendocrine tumor.Radiology case reports · 2021Article
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5 authors at 3 institutions in 1 country.
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Abstract
backgroundMetastatic neuroendocrine tumours (NETs) to the breast are very rare entities. CASE PRESENTATION: A 26-year-old lady presented with anterior neck swelling with symptoms of superior vena cava syndrome for 6 months. Imaging study revealed a mediastinal mass which was preceded with core biopsy which was consistent with high-grade small cell NETs. Despite second-line adjuvant chemotherapy and radiotherapy, her disease became advanced which was confirmed via restaging scan. There were bilateral breast lesions discovered during the scan which was deemed to be metastatic NETs histologically. Despite prompt initiation of treatment, she succumbed 1 year after the radiotherapy due to disease progression.
conclusionHigh suspicion of an index is needed for diagnosis when patients with known primary NETs present with suspicious breast lesions. Triple assessment is mandatory, however histopathology assessment and immunohistochemistry staining are the mainstay of diagnosis.
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