Evidence map›Paper›PMID 33250899›Full record

ArticleFrontiers in immunology2020

Early Cytokine Induction Upon

Ulrike Kolbe, Buqing Yi, Tanja Poth, Amy Saunders, Sébastien Boutin, Alexander H Dalpke

Abstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Exploring the Role ofACS infectious diseases · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. mBio · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Review
  12. Article
  13. Article
  14. Review
  15. Antioxidant and Anti-Inflammatory Effects of Thyme (Antioxidants (Basel, Switzerland) · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Commensal Bacteria in the Cystic Fibrosis Airway Microbiome ReduceFrontiers in cellular and infection microbiology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ulrike KolbeDepartment of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.
Buqing YiInstitute of Medical Microbiology and Hygiene, Technische Universität Dresden, Dresden, Germany.
Tanja PothCMCP-Center for Model System and Comparative Pathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Amy SaundersDivision of Infection, Immunity and Respiratory Medicine, School of Biological Science, Faculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Sébastien BoutinDepartment of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.
Alexander H DalpkeDepartment of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breathing allows a multitude of airborne microbes and microbial compounds to access the lung. Constant exposure of the pulmonary microenvironment to immunogenic particles illustrates the need for proper control mechanisms ensuring the differentiation between threatening and harmless encounters. Discrimination between live and dead bacteria has been suggested to be such a mechanism. In this study, we performed infection studies of murine precision cut lung slices (PCLS) with live or heat-killed

Indexed as

Host-Pathogen InteractionsAnimalsBiopsyComputational BiologyCytokinesDisease Models, AnimalFlagellinGene Expression ProfilingImmunohistochemistryMiceMice, KnockoutMicrobial ViabilityPneumonia, BacterialPseudomonas aeruginosaPseudomonas InfectionsTranscriptomeCytokinesFlagellinType III Secretion Systemsinfection and immunityinnate immunitylive/dead discriminationprecision cut lung slicePseudomonas aeruginosa

Identifiers

PMID33250899
PMCPMC7673395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.