Evidence map›Paper›PMID 33250875›Full record

ArticleFrontiers in microbiology2020

Guanosine Tetraphosphate Has a Similar Affinity for Each of Its Two Binding Sites on

Angela R Myers, Danielle P Thistle, Wilma Ross, Richard L Gourse

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. (p)ppGpp is required for virulence ofInfection and immunity · 2024
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Angela R MyersDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, United States.
Danielle P ThistleDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, United States.
Wilma RossDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, United States.
Richard L GourseDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, United States.
University of Wisconsin–Madison · US

Funding

MEDCHANISM, ACTIVATION, &CONTROL OF RRNA TRANSCRIPTIONR01GM037048 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI GOURSE, RICHARD L. · 1986 to 2020
$5.9M
NIGMS NIH HHS R01 GM037048
6 · The paper itself

Abstract

During nutrient deprivation, the bacterial cell undergoes a stress response known as the stringent response. This response is characterized by induction of the nucleotide derivative guanosine tetraphosphate (ppGpp) that dramatically modulates the cell's transcriptome. In

Indexed as

bacterial transcriptionDksAomega subunitppGppRNA polymerasestringent response

Identifiers

PMID33250875
PMCPMC7676912
OpenAlexW3097245399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.