Evidence map›Paper›PMID 33250857›Full record

ReviewFrontiers in endocrinology2020

Novel Approaches for Treating Autonomously Functioning Thyroid Nodules.

Pia Pace-Asciak, Jon O Russell, Mohammad Shaear, Ralph P Tufano

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Ablative Technologies for Thyroid Nodules: A Health Technology Assessment.Ontario health technology assessment series · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Nonsurgical Management of Thyroid Nodules: The Role of Ablative Therapies.The Journal of clinical endocrinology and metabolism · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pia Pace-AsciakDivision of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Jon O RussellDivision of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Mohammad ShaearDivision of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Ralph P TufanoDivision of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States.
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign thyroid nodules are exceedingly common in the adult population. Only a small percentage of nodules are toxic or autonomously functioning thyroid nodules (AFTNs). The options clinicians have for treating the symptoms of hyperthyroidism include anti-thyroidal medications, radioactive iodine, or surgery. Depending on the patient population treated, these options may not be suitable or have inherent risks that are undesirable to the patient. On the other hand, untreated hyperthyroidism can lead to osteoporosis, atrial fibrillation, emotional lability, and neurological consequences. Thus, we present a review of two novel safe and effective approaches for treating AFTN; one surgical (transoral endoscopic thyroid surgery) and one non-surgical (radiofrequency ablation), as a means for expanding our treatment armamentarium.

Indexed as

EndoscopyHumansRadiofrequency AblationThyroid Nodulebenign thyroid noduleshyperthyroidismradiofrequency ablationtoxic nodulestransoral endoscopic thyroidectomy

Identifiers

PMID33250857
PMCPMC7673400
OpenAlexW3096311724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.