Evidence map›Paper›PMID 33250688›Full record

ArticleCase reports in gastroenterology

An Extremely Rare Presentation of an Alpha-Fetoprotein-Producing Esophageal Adenocarcinoma.

Yaser Khalid, Neethi Dasu, Debashis Reja, Herman Suga, Michael Itidiare, Kirti Dasu, Richard Walters, Richard Gordon

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Yaser KhalidDivision of Internal Medicine, Memorial Healthcare System, Hollywood, Florida, USA.
Neethi DasuDivision of Gastroenterology, Rowan University School of Medicine at Jefferson Health System, Stratford, New Jersey, USA.
Debashis RejaDivision of Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Herman SugaDivision of Internal Medicine, Rowan University School of Medicine at Jefferson Health System, Stratford, New Jersey, USA.
Michael ItidiareDivision of Gastroenterology, Rowan University School of Medicine at Jefferson Health System, Stratford, New Jersey, USA.
Kirti DasuDivision of Biology, Syracuse University, Syracuse, New York, USA.
Richard WaltersDivision of Gastroenterology, Rowan University School of Medicine at Jefferson Health System, Stratford, New Jersey, USA.
Richard GordonDivision of Hematology/Oncology, Comprehensive Cancer and Hematology Specialists, Voorhees, New Jersey, USA.
Thomas Jefferson University Hospital · USMemorial Healthcare System · USOncology Specialists · USRutgers, The State University of New Jersey · USSyracuse University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alpha-fetoprotein (AFP)-producing esophageal adenocarcinoma (EAC) is an extremely rare occurrence with very few cases reported in the literature. We report the case of a 76-year-old female who presented with progressive weakness, fatigue, and a decrease in appetite for weeks and who was found to have an AFP-producing EAC with an extraordinarily high AFP level of 46,135 ng/mL. CT angiography revealed abnormal thickening of the esophagus and multiple metastatic masses throughout the liver. Upper endoscopy revealed a large mass in the distal esophagus with extension into the stomach. Biopsy confirmed the EAC. Most cases are unsuccessfully treated with surgery and chemotherapy. Serial measurement of serum AFP may be useful for monitoring clinical status and treatment response.

Indexed as

Alpha-fetoproteinEsophageal cancerGastroesophageal reflux diseaseHepatocellular cancer

Identifiers

PMID33250688
PMCPMC7670355
OpenAlexW3093850168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.